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Migraine Disorders clinical trials

View clinical trials related to Migraine Disorders.

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NCT ID: NCT02856802 Completed - Migraine Headaches Clinical Trials

An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg)

Start date: July 11, 2016
Phase: Phase 2
Study type: Interventional

A safety and efficacy study of DFN-02 (Sumatriptan Nasal Spray 10 mg), being conducted at multiple centers in the United States.

NCT ID: NCT02848326 Completed - Clinical trials for Migraine, With or Without Aura

Efficacy, Safety, and Tolerability of Multiple Dosing Regimens of Oral Atogepant (AGN-241689) in Episodic Migraine Prevention

Start date: September 6, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

This study will evaluate the safety and tolerability of the following doses of atogepant (AGN-241689): 10 mg once daily (QD), 30 mg QD, 30 mg twice daily (BID), 60 mg QD, and 60 mg BID for the prevention of episodic migraine and will characterize the dose/response relationship.

NCT ID: NCT02847494 Completed - Migraine Clinical Trials

Corticosteroids for Acute Migraine in the Emergency Department

Start date: September 1, 2016
Phase: Phase 4
Study type: Interventional

This is an emergency department based randomized trial in which we compare two different treatment for migraine headache. The goal is to decrease the number of headache days during the week after ED discharge.

NCT ID: NCT02828020 Completed - Clinical trials for Migraine, With or Without Aura

Efficacy, Safety, and Tolerability Study of Oral Ubrogepant in the Acute Treatment of Migraine

ACHIEVE I
Start date: July 22, 2016
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy, safety, and tolerability of 2 doses of ubrogepant (50 and 100 mg) compared to placebo for the acute treatment of a single migraine attack.

NCT ID: NCT02824250 Completed - Chronic Pain Clinical Trials

Mindfulness and Migraine Research Study

M&M
Start date: March 9, 2017
Phase: N/A
Study type: Interventional

The primary aim of this study is to conduct a randomized controlled feasibility trial of MBSR for patients with moderate-to- severe migraine headache.

NCT ID: NCT02795351 Completed - Migraine With Aura Clinical Trials

Induction of Migraine Aura With Sildenafil

Start date: June 2015
Phase: Early Phase 1
Study type: Interventional

In a double blind placebo-controlled cross-over study the effect of Sildenafil on aura and migraine headache induction is tested in patient with migraine with aura.

NCT ID: NCT02794441 Completed - Migraine Clinical Trials

Oral Dexamethasone for the Treatment of Acute Migraine Recurrence in the Pediatric Emergency Department

Start date: December 2016
Phase: Phase 3
Study type: Interventional

Migraine recurrence is common amongst pediatric patients being discharged from the emergency department after treatment for migraine. Despite the commonality of migraine recurrence within the week following discharge, no known effective therapies are available in the pediatric population, though dexamethasone has been established as efficacious in the adult migraine population. The proposed study will randomly assign children and adolescents visiting the emergency department (ED) for migraine to receive either one dose of oral dexamethasone or oral placebo. Twenty patients will be recruited to this randomized, double-blind, pilot trial over a 6 month period, and the aim of the study will be to determine the feasibility and acceptability of the protocol.

NCT ID: NCT02792517 Completed - Headache, Migraine Clinical Trials

Erenumab (AMG 334) Plus Combined Oral Contraceptive Drug Interaction Study in Healthy Females

Start date: February 12, 2016
Phase: Phase 1
Study type: Interventional

A pharmacokinetic drug interaction study of erenumab and an oral contraceptive containing progestin and estrogen.

NCT ID: NCT02791997 Completed - Clinical trials for Migraine Disorders, Brain

Audition After a Lesion and in Migraine. (AuditionPostLesion)

Start date: February 6, 2015
Phase: N/A
Study type: Interventional

The project studies auditory processing after brain damage (in temporal and/or frontal areas) and in migraine. The auditory processes investigated are attention, short-term memory, sound-induced emotions. To characterize auditory deficits after brain damage or in migraine, neuropsychological assessments are combined with neurophysiological markers (Electro-encephalography: EEG, Magneto-encephalography: MEG, Magnetic Resonance Imaging: MRI).

NCT ID: NCT02766517 Completed - Migraine Disorders Clinical Trials

Biomarker Study in Participants With Migraine

Start date: September 28, 2016
Phase: Early Phase 1
Study type: Interventional

This is a study of participants with a diagnosis of migraine who completed another clinical trial NCT02163993. The participants received either LY2951742 or placebo. This study NCT02766517 will evaluate how certain biomarkers may be related to the participant's response in study NCT02163993. The study will last about five days.