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Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Microbial Colonization Clinical Trial

Official title:
Comparing Single Versus Repeat Parent-to-Child Nasal Microbiome Transplant on Seeding, Engraftment, and Diversity of the Neonatal Nasal Microbiome

Clinical Trial Summary

This study aims to determine whether a parent-to-child nasal microbiota transplant (NMT) can seed and engraft parental organisms into the neonatal microbiome and increase the neonatal microbiome diversity.

Clinical Trial Description

This parent-to-child NMT study will test the effect of an anterior nares, or nasal, microbiota transplant (NMT) on seeding, engraftment, and diversity of the neonatal microbiome. Neonates admitted to the Johns Hopkins Neonatal Intensive Care Unit (NICU) will be screened and parents will be approached for enrollment in the study. After consent and baseline screening of parents and neonates, eligible neonates will undergo an NMT. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06283355
Study type Interventional
Source Johns Hopkins University
Contact Danielle Koontz
Phone 443-287-9040
Email dkoontz1@jhmi.edu
Status Not yet recruiting
Phase Phase 1
Start date August 1, 2024
Completion date December 31, 2026
View Details
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