Microbial Colonization of Oral Probiotics

Status Recruiting

Clinical Trial Summary

The aim of this study is to evaluate the colonization efficacy of probiotic lozenges and powders containing specific prebiotics in healthy adults

Clinical Trial Description

This is a double-blind, randomized controlled colonization pilot study with no cross over to evaluate the colonization efficacy of lozenges and powders containing two different commercially available probiotic bacteria (S. salivarius K12 ) or S. salivarius M18 with or without 2 different prebiotic sugars or their combinations. Participants will be randomly assigned to one of the 12 groups consuming probiotic lozenge or powder containing Streptococcus salivarius K12 or S. salivarius M18 with or without prebiotics (e.g. sugars that may promote probiotic activity) over a seven day period. Saliva samples will be collected at predetermined time points pre and post intervention. Colonisation efficacy will be determined by enumerating the probiotic in the saliva samples using standard microbiological techniques. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05375383
Study type	Interventional
Source	BLIS Technologies Limited
Contact	John D Hale, PhD
Phone	+6434740988
Email	john.hale@blis.co.nz
Status	Recruiting
Phase	N/A
Start date	June 15, 2022
Completion date	September 15, 2022

View Details

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