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Intestinal Microbiome Dynamics in Solid Organ and Stem Cell Transplant Recipients

Microbial Colonization Clinical Trial

Official title:
Intestinal Microbiome Composition Dynamics Over the Course of Kidney Transplantation, Liver Transplantation, Allogeneic Hematopoietic Stem Cells and Mesenchymal Stem Cells Transplantation

Clinical Trial Summary

This is a pilot study designed to investigate the alterations in the gut microbiome that occur during the course of kidney transplantation, liver transplantation, allogeneic hematopoietic stem cells and mesenchymal stem cells transplantation in association with the clinical outcomes.

Clinical Trial Description

This is a pilot study designed to investigate the dynamic changes in the intestinal microbiome that occur during the course of kidney transplantation, liver transplantation, allogeneic HSCs and mesenchymal stem cells transplantation. Four patient cohorts will be followed. Cohort A: patients receiving kidney transplantation. Cohort B: patients receiving hematopoietic stem cells transplantation. Cohort C: patients receiving mesenchymal stem cells transplantation. Cohort D: patients receiving liver transplantation. Included participants are defined as patients with at least three analyzable stool samples including a baseline sample before the transplantation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04281797
Study type Observational
Source Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology
Contact
Status Enrolling by invitation
Phase
Start date January 1, 2020
Completion date June 30, 2023
View Details
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