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Inflammation in Methamphetamine and STIs (IMSTI) — IMSTI  

Methamphetamine-dependence Clinical Trial

Official title:
Effects of Methamphetamine Use on Risk Behavior, Systemic and Mucosal Inflammation, and Sexually Transmitted Infection (STI)/HIV Risk Among Men Who Have Sex With Men

Clinical Trial Summary

This clinical trial aims to investigate the effects of a decline in methamphetamine use on rectal inflammatory cytokine levels, substance use contexts, and HIV/STI risk behavior. This clinical trial also seeks to evaluate joint effects of methamphetamine use and rectal gonorrhea/chlamydia infection on rectal inflammatory cytokine levels. The proposed trial will consist of 40 MSM, half with rectal gonorrhea/chlamydia infection at enrollment (n=20), with methamphetamine use disorder that will receive contingency management for methamphetamine reduction. Following baseline measurement, participants will be observed over the course of 8 weeks, where participants will complete behavioral surveys, provide urine for drug testing, and rectal samples for measurement of rectal inflammatory cytokine levels.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05162391
Study type Interventional
Source University of California, Los Angeles
Contact Cherie Blair, MD, PhD
Phone 323-461-3106
Email cherieblair@mednet.ucla.edu
Status Recruiting
Phase N/A
Start date May 31, 2022
Completion date June 30, 2027
View Details
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