Soft Tissue Sarcoma Clinical Trial
Official title:
A Pilot Study of Gemcitabine Plus High-Dose Ascorbate in Locally Advanced Unresectable or Metastatic Soft Tissue and Bone Sarcomas Including Adolescents
The purpose of this research study is to see if a high dose of ascorbate (Vitamin C), in combination with the chemotherapy drug gemcitabine, is safe and effective in adolescents with locally advanced unresectable or metastatic soft tissue and bone sarcomas
The primary objective of the expansion cohort of this pilot study is to evaluate preliminary evidence of anti-tumor activity of intravenous ascorbate in combination with gemcitabine as assessed by overall response rate to inform a subsequent Phase II trial. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
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Phase 1/Phase 2 | |
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||
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| Completed |
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Phase 2 | |
| Completed |
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Phase 3 |