Isolation of Circulating Tumor Cells Using a Novel EMT-Based Capture Method — CTC-EMT  

Metastatic Progressive Castration-resistant Prostate Cancer Clinical Trial

Official title: Isolation of Circulating Tumor Cells Using a Novel EMT-Based Capture Method

Status Completed

Clinical Trial Summary

The primary objective of the preliminary lead-in study is to determine whether circulating tumor cells in patients with metastatic progressive castration-resistant prostate cancer or metastatic progressive breast cancer can be captured using a novel mesenchymal-marker based ferrofluid (N-cadherin or O-cadherin based).

The primary objective of each comparative cohort (second stage, prostate cancer) is to compare the non-detection rate of circulating tumor cells between the standard and novel methods.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Metastatic Progressive Breast Cancer
• Metastatic Progressive Castration-resistant Prostate Cancer
• Neoplastic Cells, Circulating
• Prostatic Neoplasms

• NCT number: NCT02025413
• Study type: Interventional
• Source: Duke University
• Status: Completed
• Phase: N/A
• Start date: November 2011
• Completion date: December 2015