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Clinical Trial Summary

This is an Phase Ib/2 study, single arm, single cohort study to determine the safety and tolerability of Dupilumab with PD-(L)1 blockade for patients with relapsed/refractory metastatic NSCLC. For Phase 2, to determine the effect of adding IL-4Ra blockade to PD-(L)1 blocking agents in patients with relapsed/refractory NSCLC, who have progressed on prior PD-(L)1 agents


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05013450
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact Thomas Marron, MD PhD
Phone 212-824-9472
Email thomas.marron@mssm.edu
Status Recruiting
Phase Phase 1/Phase 2
Start date September 10, 2021
Completion date December 2024

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