Other Clinical Trial - Phase II Trial of Sorafenib (Nexavar) in Patients

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Metastatic Anaplastic Thyroid Cancer
Metastatic Differentiated Thyroid Cancer
Metastatic Medullary Thyroid Cancer
Metastatic Poorly Differentiated Thyroid Cancer
Thyroid Carcinoma, Anaplastic
Thyroid Diseases
Thyroid Neoplasms

See also
Status	Clinical Trial	Phase
Suspended	`NCT01927887` - Pre-Operative Nodal Staging of Thyroid Cancer Using Ultra-Small Superparamagnetic Iron Oxide Magnetic Resonance Imaging (USPIO MRI): Preliminary Study	N/A
Recruiting	`NCT04877613` - GFRα4 CAR T Cells in MTC Patients	Phase 1
Completed	`NCT02109250` - CAPRELSA® REGISTRY: a Belgian Registry to Evaluate the Use of Vandetanib (Caprelsa®) in Current Clinical Practice	N/A

See also

Status

Clinical Trial

Phase

Suspended

NCT01927887 - Pre-Operative Nodal Staging of Thyroid Cancer Using Ultra-Small Superparamagnetic Iron Oxide Magnetic Resonance Imaging (USPIO MRI): Preliminary Study

N/A

Recruiting

NCT04877613 - GFRα4 CAR T Cells in MTC Patients

Phase 1

Completed

NCT02109250 - CAPRELSA® REGISTRY: a Belgian Registry to Evaluate the Use of Vandetanib (Caprelsa®) in Current Clinical Practice

N/A

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT00654238
Study type	Interventional
Source	University of Pennsylvania
Contact
Status	Completed
Phase	Phase 2
Start date	February 2006
Completion date	March 2011

Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms