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Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Colorectal Cancer Clinical Trial

Official title:
Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Clinical Trial Summary

This research study is a randomized controlled trial that will observe changes in microbiome activity, changes in chemotherapy toxicity, and any changes in treatment outcomes between two groups of participants undergoing chemotherapy with either early-stage or metastatic colorectal cancer. The names of the study groups involved in this study are: - Exercise - Waitlist Control

Clinical Trial Description

This research study is a single-center, two-armed, randomized controlled trial that will observe changes in microbiome activity, changes in chemotherapy toxicity, and any changes in treatment outcomes between two groups of participants undergoing chemotherapy with either early-stage or metastatic colorectal cancer. Participants will be randomly assigned to one of two groups: Group A: Exercise group (EXE) vs. Group B: Waitlist control group (WC). Randomization means that a participant will be placed into one of the study groups by chance. The research study procedures include screening for eligibility, blood tests, stool samples, and survey questionnaires. Participation in this research study will last up to 6 months. It is expected that about 84 people will take part in this research study. The American Cancer Society is providing funding for this research study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06202183
Study type Interventional
Source Dana-Farber Cancer Institute
Contact Christina Dieli-Conwright, MPH, PhD
Phone 617-582-8321
Email ChristinaM_Dieli-Conwright@dfci.harvard.edu
Status Not yet recruiting
Phase N/A
Start date June 2024
Completion date July 31, 2027
View Details
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