Curcumin in Combination With 5FU for Colon Cancer

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to test the safety and find the response rate of combining the dietary supplement, curcumin, with the standard of care, FDA-approved chemotherapy drug 5-fluorouracil (5FU, Adracil) and see what effects (good and bad) that the combined treatments have on colon cancer.

Clinical Trial Description

Confirm clinical safety and identify clinical response rate of combination treatment with curcumin and 5FU in chemorefractory CRC patients. To determine whether curcumin administration induces systemic alterations in inflammatory and epigenetic biomarkers in patients with chemoresistant metastatic colorectal cancer (CRC). To correlate altered biomarker findings with clinical response according to RECIST V1.1 and survival criteria. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02724202
Study type	Interventional
Source	Baylor Research Institute
Contact
Status	Active, not recruiting
Phase	Early Phase 1
Start date	March 2016
Completion date	June 13, 2020

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