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NCT00146029 Clinical Trial

Companion Pharmacogenetic Study to UMCC 9900/9901

Metastatic Breast Cancer Clinical Trial

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT00146029
Other study ID # UMCC 3-27
Secondary ID
Status Terminated
Phase N/A
First received September 1, 2005
Last updated March 24, 2008

Study information
Verified date March 2008
Source University of Michigan Cancer Center
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

The purpose is to examine the original breast tumor material to see how much of a metabolizing enzyme (CYP3A4) is present in tumor material. The researchers want to see if this is in any way associated with how the patient responded to docetaxel. They also want to examine the genes in the tumor that are responsible for the production of CYP metabolizing enzymes, to see if they are normal or if they have polymorphisms, or change compared to 'normal' CYP metabolizing enzymes.

Recruitment information / eligibility
Status Terminated
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Patients who participated on UMCC 9900/9901

- Living patients must give written informed consent

Exclusion Criteria:

- No tumor block tissue available

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

Locations
Country Name City State
United States University of Michigan Cancer Center Ann Arbor Michigan

Sponsors (1)
Lead Sponsor Collaborator
University of Michigan Cancer Center

Country where clinical trial is conducted

United States, 

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