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Clinical Trial Summary

A Phase 1 study to evaluate the safety, tolerability, PK, immunogenicity, pharmacodynamics, and preliminary antitumor activity of AK114.

Clinical Trial Description

This is a first-in-human (FIH), Phase 1a, multicenter, open-label, single-arm dose-escalation study of AK114 to evaluate the safety, tolerability, PK, pharmacodynamics, antitumor activity and immunogenicity in adult subjects with advanced or metastatic solid tumors. The study is comprised of dose escalation phase. Approximately 30 subjects will be treated in this study. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05200273
Study type Interventional
Source Akeso
Contact Alex HL Wong, MMedSc
Phone +86(0760)89873999
Status Not yet recruiting
Phase Phase 1
Start date March 15, 2022
Completion date December 30, 2023

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