Clinical Trials Logo

Metaplastic Breast Carcinoma clinical trials

View clinical trials related to Metaplastic Breast Carcinoma.

Filter by:
  • None
  • Page 1

NCT ID: NCT05660083 Recruiting - Clinical trials for Metastatic Breast Cancer

Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

Start date: January 12, 2023
Phase: Phase 2
Study type: Interventional

This is a research study to test the safety and effectiveness of using the drug alpelisib together with chemotherapy (nab-paclitaxel) and a drug called L-NMMA in patients with HER2 negative metastatic or locally advanced metaplastic breast cancer, who have not responded to previous treatments. Participants in this study in addition to the standard care chemotherapy will also receive the drug alpelisib and L-NMMA. The therapies will be administered every 3 weeks (1 cycle) until disease progression, toxicity or until the participant withdraws from the study. The nab-paclitaxel chemotherapy will be administered intravenously on Day 1 of the 3 week cycles. Participants will take the drug alpelisib by mouth once daily at a dose determined by a safety study and the drug L-NMMA will be given intravenously on days 1 to 5 of the 3 week cycles.

NCT ID: NCT04549584 Terminated - Clinical trials for Metaplastic Breast Carcinoma

Neoadjuvant Chemotherapy Response in Metaplastic Carcinoma of Triple Negative Breast Cancer

NEO-SMART
Start date: October 1, 2020
Phase:
Study type: Observational [Patient Registry]

prospective study for response of neoadjuvant chemotherapy in metaplastic carcinoma of triple negative breast cancer