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Clinical Trial Summary

Previous research shows that gypenoside could keep blood lipid and blood sugar under control in an effective way. In this study, we intend to explore whether gypenosides have clinical improvement effects on metabolic diseases such as diabetes, hyperlipidemia, and non-alcoholic fatty liver and their cardiovascular protective potential. It is designed to recruit 150 patients with metabolic syndrome diagnosed who meet the criteria for enrollment, and randomly divide them into three groups. Gynostemma powder, with two different saponins content (12% and 8%) from Pingli County, Shaanxi Province, and spinach powder with almost no saponins were used to conduct the intervention on patients. Patients will be followed up regularly at the beginning of each month from the first enrollment until the third month. At each follow-up, data of patient's anthropometric indicators as well as clinical inspection indicators related to metabolism (blood routine, liver function, etc.) will be recorded. In addition, patient's blood, hair, urine, and stool samples will be collected to further explore the mechanism of diseases.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05118698
Study type Interventional
Source First Affiliated Hospital Xi'an Jiaotong University
Contact Yanan Wang, professor
Phone 0086-13359242141
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date November 25, 2021
Completion date December 31, 2022

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