Carotid Atherosclerotic Plaque Load and Neck Circumference

Metabolic Syndrome Clinical Trial

Official title:

Determination of Carotid Atherosclerotic Plaque Load and Neck Circumference in Cranial CT Angiography With Machine Learning Method and Their Relationship With Each Other

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05040958
• Other study ID #: CAPNET
• Status: Recruiting
• Start date: September 8, 2021
• Est. completion date: March 28, 2022

Study information

• Verified date: September 2021
• Source: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
• Contact: Elif Yildirim Ayaz, M.D.
• Phone: +905325148300
• Email: drelifyildirim[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this study is to establish a deep learning model to automatically detect the presence and scoring of carotid plaques in neck CTA images, and to determine whether this model is compatible with manual interpretations.

Description:

Modeling CTA images for carotid artery segments with deep learning method and automatic carotid plaque presence and scoring will be useful and beneficial in clinical practice. The aim of this study is to establish a deep learning model to automatically detect the presence and scoring of carotid plaques in neck CTA images, and to determine whether this model is compatible with manual interpretations.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 300
• Est. completion date: March 28, 2022
• Est. primary completion date: March 28, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• 18 years or older

• Having cranial CTA withdrawn

• Having blood lipids, HbA1c, blood glucose, AST, ALT measured in 3 months before and 3 months after cranial CTA

Exclusion Criteria:

• Thyroid disease

• Having had neck surgery

• Use of corticosteroids for more than 6 months

• Presence of lymph nodes in the anterior neck

• Hypertrophy of neck muscles

Related Conditions & MeSH terms

• Atherosclerosis
• Atherosclerosis of Artery
• Machine Learning
• Metabolic Syndrome
• Plaque, Atherosclerotic

Locations

Country	Name	City	State
Turkey	Istanbul MEdeniyet University Göztepe Prof. Dr. Süleyman Yalçin City Hospital	Kadiköy	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation of the machine learning model and manual interpretation	Evaluation of the correlation of the presence of plaque in the carotid segments with manual interpretation in the model obtained by machine learning method	1 day