Metabolic Syndrome Clinical Trial
Official title:
Phospholipid and Sphingolipid Composition of High-density Lipoproteins (HDL) in Obese Non-diabetic Patients With Metabolic Syndrome
HDL in obese non-diabetic patients show major alterations in their function and thus their
cardio-protective effects. These alterations could be explained by the quantitative and
qualitative anomalies in the phospholipids and sphingolipids in the HDL. These molecules play
a major role in HDL function and probably present early modifications in obesity, even before
the onset of glycaemia deregulation.
The aim of this study is to show the presence of qualitative and quantitative modifications
of phospholipids and sphingolipids in HDL from obese patients compared with HDL from
non-obese controls.
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