Metabolic Syndrome Clinical Trial
NCT number | NCT01589224 |
Other study ID # | KoreaHealth_MDCT |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | April 24, 2012 |
Last updated | October 12, 2015 |
Start date | May 2012 |
Verified date | April 2012 |
Source | Korea University |
Contact | n/a |
Is FDA regulated | No |
Health authority | South Korea: Institutional Review Board |
Study type | Observational |
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as direct regulators of atherosclerosis. Therefore, the investigators examine the correlation of various metabolic risk factors including adipokines and hepatokines with coronary atherosclerosis measured by coronary MDCT in apparently healthy people.
Status | Completed |
Enrollment | 150 |
Est. completion date | |
Est. primary completion date | August 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 20 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Apparently healthy people who underwent medical routine check up in Korea Health Promotion Center. - age > 20 years Exclusion Criteria: - History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization) - Diabetes - Stage 2 hypertension - Severe renal or hepatic disease |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | korea University Guro Hospital | Seoul |
Lead Sponsor | Collaborator |
---|---|
Korea University |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT | to examine the correlation of serum concentration of various adipokine such as adiponectin, resistin, A-FABP with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score | 3month | No |
Secondary | relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT | to examine the correlation of serum concentration of various hepatokines such as FGF-21, fetuin- A and selenoprotein P with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score | 3months | No |
Secondary | the correlation of various inflammatory markers with coronary atherosclerosis | 3months | No |
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