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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01589224
Other study ID # KoreaHealth_MDCT
Secondary ID
Status Completed
Phase N/A
First received April 24, 2012
Last updated October 12, 2015
Start date May 2012

Study information

Verified date April 2012
Source Korea University
Contact n/a
Is FDA regulated No
Health authority South Korea: Institutional Review Board
Study type Observational

Clinical Trial Summary

Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as direct regulators of atherosclerosis. Therefore, the investigators examine the correlation of various metabolic risk factors including adipokines and hepatokines with coronary atherosclerosis measured by coronary MDCT in apparently healthy people.


Recruitment information / eligibility

Status Completed
Enrollment 150
Est. completion date
Est. primary completion date August 2012
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria:

- Apparently healthy people who underwent medical routine check up in Korea Health Promotion Center.

- age > 20 years

Exclusion Criteria:

- History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)

- Diabetes

- Stage 2 hypertension

- Severe renal or hepatic disease

Study Design

Observational Model: Cohort, Time Perspective: Prospective


Related Conditions & MeSH terms


Locations

Country Name City State
Korea, Republic of korea University Guro Hospital Seoul

Sponsors (1)

Lead Sponsor Collaborator
Korea University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type Measure Description Time frame Safety issue
Primary relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT to examine the correlation of serum concentration of various adipokine such as adiponectin, resistin, A-FABP with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score 3month No
Secondary relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT to examine the correlation of serum concentration of various hepatokines such as FGF-21, fetuin- A and selenoprotein P with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score 3months No
Secondary the correlation of various inflammatory markers with coronary atherosclerosis 3months No
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