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Antipsychotic Medicine and Metabolic Syndrome — AMMS1  

Metabolic Syndrome Clinical Trial

Official title:
Changes in Enteroendocrine and Neuroendocrine Axes in Patients With Weight Gain After Treatment With Antipsychotics

Clinical Trial Summary

The purpose of the study is to determine whether antipsychotic treatment is influence psychiatric patients due to endocrine and metabolic status and a quality of life.

The investigators expect, that 30-50% of patients will show pharmacon - gene induced weight gain (> 7% of initial bodyweight) while the rest of patients will maintain unaltered bodyweight.

Clinical Trial Description

The primary aim of this study is to investigate status of neuro-and enteroendocrine axes with focus on beta - cell function in relation to insulin resistance, lipid profile abnormalities and inflammations adipokins in patients during treatment with antipsychotics (AP) in relation to weight gain.

The second aim is to evaluate the connection between weight gain and patients´ own perception of their quality of life and health. ;

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00627757
Study type Observational
Source Glostrup University Hospital, Copenhagen
Contact Henrik Lublin, MD DMSc
Phone 045-43233540
Email henlub01@glo.regionh.dk
Status Recruiting
Phase N/A
Start date February 2008
Completion date December 2010
View Details
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