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Metabolic Syndrome clinical trials

View clinical trials related to Metabolic Syndrome.

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NCT ID: NCT00508157 Terminated - Schizophrenia Clinical Trials

A Phase 4 Study to Assess the Effects of Aripiprazole Versus Other Atypical Antipsychotics in the Treatment of Schizophrenic Patients With Metabolic Syndrome

Start date: November 2007
Phase: Phase 4
Study type: Interventional

258 patients who have been treated for at least 3 months with oral olanzapine, risperidone or quetiapine in the treatment of schizophrenia and currently presenting with metabolic syndrome, will be randomized to: i) aripiprazole for 16 weeks, with flexible dosing within a range of 10 to 30 mg once daily (QD); or ii) continue for 16 weeks on the same atypical antipsychotic treatment prior to the study enrollment.

NCT ID: NCT00491400 Terminated - Diabetes Mellitus Clinical Trials

Effect of a Fibrate and a Statin on Endothelial Dysfunction

Start date: September 2005
Phase: N/A
Study type: Interventional

The study will compare the effect of atorvastatin to the effect of fenofibrate on endothelial function in patients with diabetes mellitus or the metabolic syndrome.

NCT ID: NCT00477191 Terminated - Obesity Clinical Trials

Effects of TNF-alpha Antagonism (Etanercept) in Patients With the Metabolic Syndrome and Psoriasis

Start date: May 2007
Phase: N/A
Study type: Interventional

People with psoriasis have significantly higher rates of obesity, diabetes, heart failure and high blood pressure than the general public. The purpose of this study is to determine how substances produced in the fat (inflammatory markers) relate to the risk of heart disease in people with the metabolic syndrome and psoriasis. People with metabolic syndrome have insulin resistance, increased waist size, high blood pressure, or high cholesterol.

NCT ID: NCT00465296 Terminated - Metabolic Syndrome Clinical Trials

Ppar-Gamma EliminAtes Restenosis Longevity Study: PEARLS

Start date: January 2006
Phase: Phase 3
Study type: Interventional

The primary objective of this clinical trial is to assess the efficacy of rosiglitazone on bare metal stent (BMS) in-stent restenosis measured as late lumen loss in patients with metabolic syndrome. The secondary parameter for evaluation of efficacy is binary restenosis. The tertiary objective will be to assess the effect of rosiglitazone on major cardiac events (MACE; death, MI, CABG, and target vessel revascularization). The occurrence of in-stent restenosis for patients with metabolic syndrome who receive a DES in a non-target lesion will be assessed angiographically at 9 months.

NCT ID: NCT00438321 Terminated - Metabolic Syndrome Clinical Trials

Effect of Increasing Testosterone on Insulin Sensitivity in Men With the Metabolic Syndrome

Start date: September 2006
Phase: Phase 1
Study type: Interventional

The purpose of the study is to examine the effect of testosterone treatment on insulin in men with the metabolic syndrome with testosterone levels at or below the lower end of the normal range.

NCT ID: NCT00229229 Terminated - Obesity Clinical Trials

Comparison of 4 Diets in the Management of Overweight Patients With Vascular Disease

Start date: September 2004
Phase: Phase 4
Study type: Interventional

Type 2 diabetes can be prevented by lifestyle changes in high-risk subjects. However, controversies exist on nutritional management of diabetes. Recent data suggests that glucose and insulin responses are affected by not only the quality, but the quantity of carbohydrate consumed. This is referred to as glycemic load. To date, there have not been any prospective randomized studies which examine the utility of a low glycemic load diet. The purpose of the proposed study is to compare the effectiveness of a Canada Food Guide Diet with a low glycemic load diet on blood sugar control in overweight type 2 diabetics.