Effects the Glycemic Index on Metabolic Risk Markers

Status Completed

Clinical Trial Summary

Recent population studies have shown that the glycemic index (GI) of food products is positively associated with the risk of developing type 2 diabetes and cardiovascular disease (CVD). In the pathogenesis of type 2 diabetes and CVD, inflammatory processes play a pivotal role. In a previous intervention study (11 weeks), however, we found no effects of lower-GI vs. higher-GI diets on fasting inflammatory markers in subjects with increased risk of developing the metabolic syndrome. People, however, spent most of their time in the postprandial period. Therefore, there is a need to study the postprandial effects of low-GI vs. high-GI diets. In addition, it needs to be emphasized the GI is derived from studies in lean subjects, while especially overweight and obese people suffer from metabolic aberrations related to the development of type 2 diabetes and CVD. AIM: To investigate in obese subjects the postprandial effects of a low-GI vs. high-GI food product on metabolic risk markers. A second research objective is to compare these effects with those in lean subjects.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Metabolic Syndrome X

Clinical Trial Details

NCT number	NCT00695825
Study type	Interventional
Source	Maastricht University Medical Center
Contact
Status	Completed
Phase	N/A
Start date	April 1, 2006
Completion date	December 31, 2008

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT02702375` - Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases	N/A
Completed	`NCT02649348` - Effects of Prehabilitation in Gastric Cancer Patients With Metabolic Syndrome on Perioperative Outcome	N/A
Completed	`NCT02918422` - Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption	N/A
Completed	`NCT02459691` - Culturally-adapted Diabetes Prevention Lifestyle Intervention for Latinos (E-LITE Latinos)	N/A
Completed	`NCT02356952` - Effect of a Low Glycemic Index on Metabolic Syndrome	N/A
Completed	`NCT02337933` - Effect of Ursolic Acid Administration on Insulin Sensitivity and Metabolic Syndrome	Phase 2
Completed	`NCT02402985` - Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics	N/A
Completed	`NCT01694056` - Soy Protein Intake and the Metabolic Syndrome	N/A
Completed	`NCT00344903` - Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort	N/A
Recruiting	`NCT00408824` - Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)	N/A
Completed	`NCT00362908` - Effects of Low and Moderate Fat Diets on Lipids, Inflammation and Vascular Reactivity in the Metabolic Syndrome	N/A
Completed	`NCT00395486` - ROMEO (Rosuvastatin in Metabolic syndrOme)	Phase 4
Completed	`NCT00140816` - Dairy Products and Metabolic Effects (Norwegian Part)	N/A
Completed	`NCT00101517` - Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease	N/A
Completed	`NCT00455325` - Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS)	Phase 2
Completed	`NCT00166036` - Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells	Phase 2
Recruiting	`NCT00177892` - Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress	N/A
Completed	`NCT00074451` - Genomewide Search for Loci Underlying Metabolic Syndrome
Completed	`NCT00073775` - Epidemiology of Stress and the Metabolic Syndrome	N/A
Completed	`NCT00200993` - Peripheral Effects of Exercise on Cardiovascular Health (STRRIDE I)	Phase 2