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Evaluation of Arginine in Periodontal and Cardiovascular Disease

Metabolic Disorder Clinical Trial

Official title:
Analysis of Serum and Salivary ADMA-Arginine Levels in Patients With Periodontal and Cardiovascular Diseases

Clinical Trial Summary

Asymmetric dimethylarginine (ADMA) plays a key role in endothelial function and may be a link for the known interaction of periodontitis and coronary heart disease (CHD). The investigators compared the impact of gingival health, periodontitis (CP), CHD or of both diseases (CP+CHD) on saliva and serum ADMA levels.

Clinical Trial Description

The aim of this study was to evaluate a possible association between both saliva and serum ADMA levels in patients with CP and with CHD and if the serum ADMA levels are mediated by serum CRP. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03873948
Study type Observational
Source University of Messina
Contact
Status Completed
Phase
Start date January 6, 2014
Completion date March 1, 2019
View Details
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