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Brown Adipose Tissue as a Therapeutic for the Metabolic and Cardiac Dysfunction With Senescence (BATSR) — BATSR  

Metabolic Diseases Clinical Trial

Official title:
Brown Adipose Tissue as a Therapeutic for the Metabolic and Cardiac Dysfunction With Senescence (BATSR)

Clinical Trial Summary

The goal of this study is to define the effect of aging on brown adipose tissue mass in a cohort of older sedentary and older athlete adults.

Clinical Trial Description

Brown adipose tissue is a thermogenic tissue that contains large capacity to dissipate energy as heat. When activated by either cold-stimulation or increasing the amount of brown adipose tissue by transplantation, brown adipose tissue increases energy expenditure, decreases plasma glucose and lipids and improves systemic metabolism. Brown adipose tissue has great potential as a therapeutic target to combat both metabolic and cardiovascular disease, but brown adipose tissue decreases with age. The objective of this study is to define the effect of aging on brown adipose tissue mass in a cohort of older sedentary and older athlete adults. Studying the role of brown adipose tissue will potentially help us understand and prevent an accelerated aging process, which will help researchers better understand metabolic and cardiac health in the elderly. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04168580
Study type Interventional
Source AdventHealth Translational Research Institute
Contact Recruitment Department
Phone 407-303-7100
Email Fh.tri.recruitment@adventhealth.com
Status Recruiting
Phase Phase 1/Phase 2
Start date November 7, 2019
Completion date December 2024
View Details
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