The Effects of Amino Acid Supplement During Acute Inflammation.

Status Completed

Clinical Trial Summary

The purpose of the study is to investigate the metabolic effects during acute inflammation with and without the nutritional supplement of amino acids.

E. Coli Endotoxin (LPS, lipopolysaccharide) is used to initiate an inflammatory response.

The study is an interventional randomized placebo study including 8 healthy male subjects. Each subject participates 3 times (different days) and are given one of following interventions:

- Placebo (NaCl)

- Endotoxin, US standard reference E.Coli + Placebo (NaCl)

- Endotoxin, US standard reference E.Coli + Amino acids (intravenously)

It is our hypothesis that the nutritional intervention during acute inflammation plays an important role in lipid and protein metabolism.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01705782
Study type	Interventional
Source	University of Aarhus
Contact
Status	Completed
Phase	N/A
Start date	October 2012
Completion date	December 2013

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