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Clinical Trial Summary

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Merkel Cell Carcinoma (MCC) who have failed treatment with at least one anti-PD-1 or anti-PD-L1 immunotherapy or in combination with avelumab in MCC patients who are anti-PD-1 or anti-PD-L1 treatment naïve. Inhibition of MDM2 is a novel mechanism of action in MCC.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03787602
Study type Interventional
Source Kartos Therapeutics, Inc.
Contact John Mei
Phone 650-542-0136
Email jmei@kartosthera.com
Status Recruiting
Phase Phase 1/Phase 2
Start date March 19, 2019
Completion date August 2025

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