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Mental Disorders clinical trials

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NCT ID: NCT00465920 Recruiting - Schizophrenia Clinical Trials

Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis

mCBT
Start date: May 2007
Phase: Phase 2
Study type: Interventional

In the last decade cognitive behavioural therapy (CBT) approaches for patients with schizophrenia have been developed, which where especially designed to reduce severity of positive symptoms, readmission rates, treatment non-compliance and disability. Although CBT addresses the key problems of early onset psychoses (EOP)treatment and first evaluations of CBT in adults with schizophrenia are promising, no experience with CBT in adolescents with EOP are available. Therefore the present study is conducted to develop a modified CBT (mCBT) for adolescents with EOP, to explore its acceptance and feasibility and to provide data for a realistic estimation of achievable effect size. Patients are randomized to receive either mCBT+TAU or TAU over a 9 month period. mCBT is an individual outpatient treatment of 20 session and 5 psychoeducational sessions with parents. Follow-ups for two years every 6 months are planned.

NCT ID: NCT00312676 Recruiting - Epilepsy Clinical Trials

Compare Tolerability of an Overnight Switch to Gradual Switch Between Two Different Forms of Depakote

Start date: March 2006
Phase: Phase 4
Study type: Interventional

The hypothesis is that the characteristics of extended release Depakote will allow overnight conversion of immediate release to extended release form of Depakote. This has been tested successfully in younger patients but not in individuals over the age of 60. We will include individuals between 60 and 80 years old.

NCT ID: NCT00192751 Recruiting - Clinical trials for Patients Diagnosed With Severe Mental Illness

From Compliance to Alliance: Engaging Psychiatric Patients in Illness Management

Start date: February 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the benefit and impact on relapse prevention,adherence to treatment and general health indices of participation in psycho-eduational group intervention among psychiatric patients with severe mental illness,recently discharged from inpatient services.

NCT ID: NCT00172887 Recruiting - Mental Disorders Clinical Trials

Needs Assessment of Long-Term Care for Psychiatric Patients

Start date: March 2005
Phase: N/A
Study type: Observational

The quantity and quality of inpatient services for persons with psychiatric illness have been enhanced in the last two decades. Following the enforcement of nationwide health insurance and the Physically and Mentally Disabled Citizens Protection Act, the financial pressure of medical care for psychiatric patients is relieved, and actions related to the protection of patients' human rights have been taken. Nonetheless, problems related to psychiatric illness are not limited to symptoms. Patients' daily functions are affected and it causes continuous pressure on the family. Currently, psychiatric care places more emphasis on inpatient services. Once the patient is discharged from the hospital, related psychiatric services are not widely available, which leads to symptom exacerbation, repeated hospital admissions, increased burden to the family, etc. A provision of continuous long-term care that meets the various needs of psychiatric patients is a critical issue in current psychiatric care. Based on a three-phase needs assessment model, the purpose of the study is to evaluate the needs of long-term care for psychiatric patients. The first phase will identify the current status of needs from the perspectives of patients and the family, psychiatric professionals, and the system. The second phase will identify the goals of long-term care for psychiatric patients. The goals will be identified by a nominal group, composed of experts related to the field of psychiatric long-term care. The third phase will determine the objectives of long-term care services for psychiatric patients. That is to determine the proper contents of long-term care services for the patients based on the goals identified in the previous phase. The three-phase needs assessment will be carried out in a two-year period. The results of the study will provide important information to the future planning of long-term care for psychiatric patients.

NCT ID: NCT00166764 Recruiting - Clinical trials for Psychiatric Disorders

A Study on Evaluation of Mental Health Index of Patients With Psychiatric Disorders

Start date: September 2005
Phase: N/A
Study type: Observational

Psychiatric patients under the mental impaired influences, their living function were disabled, and their social lives were handicapped consequently. Idea psychiatric treatment is to control the psychiatric symptoms in a better way, to develop efficient psychiatric adjustment, to manage living stress into a lower level, to gradually develop the meaning and value of the patients’ lives, and to obtain the satisfaction and happiness in life for them. In order to investigate the satisfaction for psychiatric patients under the current treatment and to evaluate their psychiatric health, it is necessary to measure the mental health status for the psychiatric patients, and to ensure the ideological status of psychiatric treatment. If there is a mental health measurement for the psychiatric patients, we may precisely identify the mental health levels of the patients and their mental disturbances degrees. Accordingly, we may develop efficient procedure to manage the mental health for the psychiatric patients, and to achieve the goal for the idea psychiatric treatment. In this study, we established the mental health assessment data sheet according to the clinical experiences. It includes mental health index data sheet, mental-and-physical stress response data sheet, mental sustentation data sheet, and supplemented with a general living satisfaction assessment data sheet. We will evaluate the reliability and validity of this study to ensure the usability of these data sheet in clinics. We will also recruit the continuous treated and mentally stabilized patients as subjects. After obtaining their written informed consents, we will go through these mental health assessments to discover the mental health status of these psychiatric patients, and use it as a reference to develop idea psychiatric treatment. We will use ICC test for the repeated measurement validity, Pearson r correlation coefficient within our data analyses to evaluate the validity of the same measurement, and independent t-test to assess the differences between the patient group and the society group (from previously established data files). This study result may evaluate the possible deficits existing in the traditional psychiatric treatment and may be used as a reference for the development of idea psychiatric medicine.

NCT ID: NCT00001246 Recruiting - Schizophrenia Clinical Trials

Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

Start date: June 19, 1990
Phase:
Study type: Observational

Magnetic Resonance Imaging (MRI) unlike X-rays and CT-scans does not use radiation to create a picture. MRI use as the name implies, magnetism to create pictures with excellent anatomical resolution. Functional MRIs are diagnostic tests that allow doctors to not only view anatomy, but physiology and function. It is for these reasons that MRIs are excellent methods for studying the brain. In this study, researchers will use MRI to assess brain anatomy and function in X and Y chromosome variation, healthy volunteers, and patients with a variety of childhood onset psychiatric disorders. The disorders include attention deficit disorder, autism, congenital adrenal hyperplasia, childhood-onset schizophrenia, dyslexia, obsessive compulsive disorder, Sydenham's chorea, and Tourette's syndrome. Results of the MRIs showing the anatomy of the brain and brain function will be compared across age, sex (gender), and diagnostic groups. Correlations between brain and behavioral measures will be examined for normal and clinical populations.