Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

Meniscus Injury Clinical Trial

Official title:

Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04962555
• Other study ID #: IRB00006761-2015159
• Status: Recruiting
• Start date: August 1, 2016
• Est. completion date: December 1, 2022

Study information

• Verified date: June 2021
• Source: Peking University Third Hospital
• Contact: Jia-kuo Yu, Prof.
• Phone: +86 13331031448
• Email: yujiakuo[@]126.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Through the analysis of the data of 8094 patients with knee meniscus injury before December 31, 2008 and more patients with partial meniscus resection, subtotal resection and total resection, we can understand the gender difference and ratio of medial and lateral meniscus injuries. Differences, differences in locations, differences in tearing methods, differences in surgical methods, and the course of the disease affect the meniscus injury and surgical methods, and further affect the patient's knee degeneration imaging, accompanying cartilage injury, knee osteoarthritis, Partial resection, subtotal resection and meniscus regeneration after total resection, imaging and secondary arthroscopic exploration (Second-Look) were studied.

Description:

Through the data of 8094 patients with knee meniscus injury who underwent surgery at the Institute of Sports Medicine of the Third Hospital of Beijing Medical University before December 31, 2008, and the patients who underwent meniscus suture, partial resection, subtotal resection, and total resection. Analyze and understand the influence of gender difference, ratio difference, position difference, tearing method difference, surgical method difference and disease course on the meniscus injury situation and operation method of the internal and lateral meniscus injury. Observation and research will also be conducted on reports of knee cartilage injury, knee osteoarthritis, and meniscus regeneration after partial meniscus resection, subtotal resection and total resection.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 8778
• Est. completion date: December 1, 2022
• Est. primary completion date: October 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

Before December 31, 2008, patients who underwent surgery for meniscus injury in this institute and patients who underwent meniscus suture, partial resection, subtotal resection, and total resection.

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Meniscus Injury
• Wounds and Injuries

Intervention

Procedure:
• Meniscus Suture
Patients with knee joint meniscus injury undergoing meniscus suture
• Partial meniscus resection
Patients with knee joint meniscus injury undergoing partial meniscus resection
• Subtotal meniscus resection
Patients with knee joint meniscus injury undergoing subtotal meniscus resection
• Complete meniscectomy
Patients with knee joint meniscus injury undergoing complete meniscectomy

Locations

Country	Name	City	State
China	Institute of Sports Medicine, Peking University Third Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking University Third Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Meniscus injury site	Observe the meniscus injury site during the operation, which is divided into: medial and lateral anterior horn, medial and lateral body, medial and lateral posterior horn, medial and lateral disc.	During operation
Primary	Types of Meniscus Injury	The types of meniscus injuries were observed during the operation, which were divided into longitudinal fissure, oblique fissure, spallation, radial fissure, and barrel shank tear.	During operation
Primary	Meniscus surgery method	Meniscus surgery methods include: partial resection, subtotal resection, total resection, and suture.	During operation
Primary	Cartilage damage	The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.	During operation
Primary	Cartilage damage	Second-look after operation to observe whether the cartilage is damaged. The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.	7 years after surgery
Primary	Meniscus regeneration	Second-look after operation to observe whether the meniscus is regenerating. The Meniscus regeneration is evaluated as yes or no, in which the meniscus shape is complete and no tear is defined as yes, and other conditions are defined as no.	7 years after surgery