Meniscus Repair With Simultaneous ACL Reconstruction: Clinical Outcomes，Failure Rates And Subsequent Processing

Meniscus Injury Clinical Trial

Official title:

Meniscus Repair With Simultaneous ACL Reconstruction: Clinical Outcomes，Failure Rates And Subsequent Processing

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04455516
• Other study ID #: M2020024
• Status: Completed
• Start date: March 16, 2020
• Est. completion date: May 16, 2020

Study information

• Verified date: July 2020
• Source: Peking University Third Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Our study has explored the causes of failure of meniscus repair and investigated the clinical effects of partial meniscectomy when meniscus repair failed.

Description:

Background: Meniscus repair performed during ACL reconstruction may fail and the subsequent treatment includes revision meniscal repair or partial meniscectomy.

Purpose: To retrospectively analyze the clinical outcomes of meniscus repair with simultaneous anterior cruciate ligament (ACL) reconstruction and explore the causes of failure of meniscus repair.

Methods: From May 2013 to July 2018, the clinical data of 165 patients who were treated with meniscus surgery and simultaneous ACL reconstruction by the same doctor, including 69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect. The average follow-up period was 38 (±10.5) months. Postoperative outcomes of the repair group and the partial meniscectomy group were compared. General conditions and postoperative outcomes of the failure group and the nonfailure group were compared. Seven patients in the failure group who underwent second arthroscopy were followed up for 30 (±17.4) months, and their postoperative outcomes were summarized.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 165
• Est. completion date: May 16, 2020
• Est. primary completion date: April 16, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 13 Years to 60 Years

Eligibility

Inclusion Criteria:

1. patients with intraoperatively confirmed ACL rupture combined with medial, lateral, or medial and lateral meniscal injury;

2. age <60 years

3. no history of previous ipsilateral knee meniscal injury.

Exclusion Criteria:

1. ACL rupture associated with fracture, collateral ligament injury, or complex ligament injury;

2. a history of knee surgery;

3. a significant degree of osteoarthritis.

Related Conditions & MeSH terms

• Meniscus Injury
• Rupture
• The ACL Rupture

Intervention

Procedure:
• Meniscus repair; partial meniscectomy
69 cases of meniscus repair (repair group) and 96 cases of partial meniscectomy (partial meniscectomy group), were retrospectively analyzed. The 69 patients of the repair group were divided into the nonfailure group (62 cases) and the failure group (7 cases) depending on the repair effect.

Locations

Country	Name	City	State
China	Peking University Third Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking University Third Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The result of partial meniscus resection	Clinical signs were assessed after the surgery, including swelling of the joint, tenderness at the joint line, locked-in syndrome, and positive McMurray's sign.	Two years after the surgery
Primary	International Knee Documentation Committee(IKDC)scores	The minimum is 0, the maximum is 100, and the higher the score, the better the result	Two years after the surgery
Primary	Visual analog scale (VAS) scores	The minimum is 0, the maximum is 10, and the higher the score, the worse the result	Two years after the surgery
Primary	Lysholm scores	The minimum is 0, the maximum is 100, and the higher the score, the better the result	Two years after the surgery