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Meniscectomy clinical trials

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NCT ID: NCT04972331 Recruiting - Clinical trials for Platelet-Rich Plasma

Degenerative Meniscus Without Osteoarthritis : Arthroscopic Partial Menisectomy Versus Platelet Rich Plasma (APM-PRP)

APM-PRP
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

This study compares arthroscopic partial menisectomy (APM) and platelet rich plasma (PRP) for degenerative meniscal injury of the knee. The current state of knowledge is poor. There are few comparative studies that have been performed and only on surgical treatment or rehabilitation. Moreover, these studies show contradictory results. The main objective of this study is to compare APM and PRPinfiltration, in terms of pain reduction, which is greater with the surgical technique than in the PRP infiltration group. The hypothesis of this study is that there is superiority of surgery over PRP infiltration. The main evaluation criterion is the pre-post-operative pain by a simplified numerical scale.

NCT ID: NCT04717609 Enrolling by invitation - Pain, Procedural Clinical Trials

Saphenous Nerve Block for Partial Meniscectomy

Start date: January 25, 2021
Phase: Phase 3
Study type: Interventional

Partial meniscectomy and meniscus repair are two of the most common orthopedic surgery procedures. As these procedures are being increasingly performed in ambulatory surgical centers, there has been a shift towards providing improved analgesia to ensure timely discharge, as well as preventing unwanted pain and side effects. As such, it has become common practice to use an intra-articular injection of local anesthetic to achieve post-operative pain control. However, these effects are short lived, requiring a multimodal approach to analgesia. To date, no optimal pain control strategy has been described for arthroscopic partial meniscectomy or meniscus repair. The purpose of this study is to examine the outcomes of subcutaneous saphenous nerve block with 0.5% ropivacaine at the medial femoral epicondyle/adductor hiatus plus portal 0.5% ropivacaine injection vs portal 0.5% ropivacaine injection alone for patients undergoing arthroscopic partial meniscectomy or meniscus repair.

NCT ID: NCT04644640 Completed - Meniscectomy Clinical Trials

Telerehabilitation Following Meniscectomy

Start date: November 11, 2020
Phase: N/A
Study type: Interventional

Telerehabilitation is a form of tele-treatment in which rehabilitation services are dispensed at patients' home utilizing video telecommunication services with real-time synchronous exchange of information. Since telerehabilitation was found to be equally effective as conventional therapy, it was being practiced even before the COVID times, however it was truly valuable during the lockdown. The advantages of telerehabilitation include reducing unnecessary travel to the hospital and person to person contact while maintaining social distancing. While some of the patients are truly staying at remote areas, others are unable to manage travel in the lockdown period. Telemedicine offers the opportunity to deliver rehabilitative services in the patients' home, closing geographic, physical, and motivational gaps. Punctuality on either side is also assured since the travel times are saved on both the ends. The purpose of the proposed study is to evaluate telerehabilitation vs in-person rehabilitation following Meniscectomy.

NCT ID: NCT03696836 Terminated - Clinical trials for Osteo Arthritis Knee

AIR (Artificial Implant for Medial Meniscus Replacement) Study

AIR
Start date: October 11, 2018
Phase: N/A
Study type: Interventional

The AIR Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® meniscus prosthesis system.

NCT ID: NCT03350204 Completed - Clinical trials for Osteoarthritis, Knee

Biomechanical Osteoarthritis Outcomes in Meniscectomy Patients

BOOM
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

The key aim of this study is to examine biomechanical measures associated with osteoarthritis (OA) progression in patients who have lateral and medial menisci injuries during various tasks. The likelihood is that individuals who have a meniscal injury often develop knee osteoarthritis. Therefore understanding biomechanical changes from the injury, specifically undertaking both functional and sporting activities, may provide a conservative approach to delaying or minimising the development of OA. Three-dimensional kinetic and kinematic measures will be assessed during seven tasks (walking, running, side cuts, single leg landing, small knee bend squat and isokinetic leg strength), prior to and following treatment. In addition, Strength and balance will be assessed to indicate if there is more work in the rehabilitation program that is needed for functional movement.

NCT ID: NCT02872753 Completed - Meniscectomy Clinical Trials

Intra-operative Injection of Autologous Conditioned Plasma (ACP) Following Partial Meniscectomy

ACP-MEN
Start date: July 11, 2017
Phase: Phase 4
Study type: Interventional

The aim of the present double blind controlled study is to evaluate the effects in terms of pain control and functional recovery provided by a single intra-operative injection of ACP performed at the end of arthroscopic partial meniscectomy. Patients included in this trial will be randomized in two treatment groups: the first one will receive a single injection of 3-5 cc of ACP (using a dedicated centrifuge) at the end of the arthroscopic meniscectomy, whereas the second group will be treated by surgery alone. In order to ensure the double blinding of the trial all the patients enrolled will undergo blood harvesting before anesthesia, and acp will be produced just for the patients included in ACP group. All patients will be evaluated basally, and then at 15, 30, 60, and 180 days after surgery by the following evaluation tools: IKDC (International Knee Documentation Committee) subjective, VAS (Visual Analogue Score) for pain, EQ-VAS for general Health Status, KOOS (Knee Injury and Osteoarthritis Outcome Score) and Tegner score. Furthermore, during the basal evaluation and at each follow-up visit up to 2 months, active and passive Range of Motion (ROM) of both the operated and contralateral knee were documented; also in addition, the trans-patellar circumference of both knees was registered to assess the trend of knee swelling over time. Drugs assumption during the follow-up period will be recorded for each patient. All eventual adverse events occurred during the follow-up period will be registered.

NCT ID: NCT02181426 Completed - Meniscectomy Clinical Trials

Dose Response of Ketorolac in Knee Arthroscopy

Start date: March 2012
Phase: N/A
Study type: Interventional

Ketorolac is administered as current practice to the majority of patients undergoing knee arthroscopy, the appropriate dose of ketorolac to be administered has not been evaluated.

NCT ID: NCT02136901 Completed - Osteoarthritis Clinical Trials

The VENUS Clinical Study (Verifying the Effectiveness of the NUsurface® System)

VENUS
Start date: June 2014
Phase: N/A
Study type: Interventional

The NUsurface® Meniscus Implant Randomized Study is a multi-center, prospective randomized, interventional clinical trial to test the hypothesis that the NUsurface implant is superior to the non-surgical standard of care in treating the target population.The rationale for performing this clinical study is to gather clinical data to evaluate the safety and effectiveness of the NUsurface device compared to the Standard of Care.

NCT ID: NCT02108496 Completed - Osteoarthritis Clinical Trials

Verifying the Effectiveness of the NUsurface® System

VENUS
Start date: July 2014
Phase: N/A
Study type: Interventional

The NUsurface® Meniscus Implant Randomized Study is a multi-center, prospective randomized, interventional clinical trial to test the hypothesis that the NUsurface implant is superior to the non-surgical standard of care in treating the target population.The rationale for performing this clinical study is to gather clinical data to evaluate the safety and effectiveness of the NUsurface device compared to the Standard of Care.

NCT ID: NCT01879852 Completed - Meniscectomy Clinical Trials

Muscle Weakness and Post-traumatic Knee OA

Start date: October 2008
Phase: N/A
Study type: Interventional

This is a single-center, randomized, single-blind (evaluator) study. Enrolled patients had a traumatic meniscal tear and underwent meniscectomy. The study included 6 weeks (12 visits) of standard or quadriceps intensive rehabilitation. The objective of the study was to determine the effect of quadriceps intensive rehabilitation on knee function and articular cartilage.