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Meningitis, Fungal clinical trials

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NCT ID: NCT01802385 Completed - Clinical trials for Cryptococcal Meningitis

Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis

ASTRO-CM
Start date: March 9, 2015
Phase: Phase 3
Study type: Interventional

This is a phase III trial to determine whether adjunctive sertraline will lead to improved survival 18-week survival. There was an initial phase I/II unmasked dose finding pharmacokinetic study of CSF concentrations in 172 persons conducted from August 2013 to August 2014. See NCT03002012.

NCT ID: NCT00002010 Completed - HIV Infections Clinical Trials

Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis

Start date: n/a
Phase: N/A
Study type: Interventional

The study is intended to examine the efficacy of fluconazole for the treatment of coccidioidal meningitis in patients with new onset of infection, relapse of previous infection, or failed previous therapy. Drug efficacy, safety and tolerance will be examined.