Memory, Short-Term Clinical Trial
Official title:
Ginkgo Biloba for ECT-induced Memory Deficits
Verified date | August 2008 |
Source | Medical University of South Carolina |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Electroconvulsive therapy (ECT) is an effective treatment for severe or medication-resistant depression and other psychiatric disorders. A common side effect of ECT is problems with short-term memory during treatment. This study will test whether taking ginkgo biloba (GB) prior to and during the course of ECT will lessen the effects of ECT on short-term memory.
Status | Terminated |
Enrollment | 50 |
Est. completion date | March 2005 |
Est. primary completion date | January 2005 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria - DSM-IV diagnosis of major depressive episode, unipolar or bipolar, without psychotic features - Receiving ECT for depression - Able to complete detailed neuropsychological testing Exclusion Criteria - Psychotic symptoms - Lifetime history of schizophrenia, schizoaffective disorder, or mental retardation - Diagnosis of anxiety disorder, obsessive-compulsive disorder, or eating disorder within 1 year of study entry - Delirium, dementia, or amnestic disorder - Any active general medical condition or central nervous system disease which could affect cognition or response to treatment - Diagnosis of active substance abuse or dependence within 6 months of study entry - ECT within 6 months of study entry - Known or suspected coagulation disorder - Anticoagulation or antiplatelet medications, including warfarin, aspirin, clopidogrel, and ticlopidine - Thiazide diuretics, selective serotonin reuptake inhibitors, trazodone, antipsychotic medications, herbal medications, or other nutritional supplements - Pregnancy |
Country | Name | City | State |
---|---|---|---|
United States | UMDNJ - NJ Medical School | Newark | New Jersey |
Lead Sponsor | Collaborator |
---|---|
Medical University of South Carolina | National Center for Complementary and Integrative Health (NCCIH) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Modified Mini-Mental State Examination | 2009 | ||
Primary | Rey Auditory Verbal Learning Test | 2009 | ||
Primary | Autobiographical Memory Inventory | 2003-2009 | ||
Primary | Spitzer Uniscale of Quality of Life(Uni) | 2--3-2009 | ||
Primary | Health Status Questionnaire | 2003-2009 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT06460207 -
Neurofeedback Removal of Emotional Information From Mind
|
N/A | |
Completed |
NCT01365897 -
Effectiveness of Modafinil in Improving Cognitive Performance of University Students
|
Phase 4 | |
Recruiting |
NCT06072378 -
The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans
|
N/A | |
Not yet recruiting |
NCT02401646 -
Clinical Trials for the Effects of Polygoni Multiflori Radix Complex Extract on Memory Improvement
|
Phase 4 | |
Completed |
NCT01321021 -
Influence of Losartan and Diphenhydramine on Emotional and Cognitive Functions in Healthy Human Subjects
|
N/A |