POSTOPERATIVE PAIN Clinical Trial
Official title:
Relationship Between Melatonin Level and Postoperative Analgesia Consumption in Bariatric Surgery Patients.
Bariatric surgical procedures are associated with low short-term mortality and may be
associated with long-term reductions in all-cause, cardiovascular, and cancer-related
mortality. This surgeries are major surgeries include risk of mortality still.
Melatonin is a hormone secreted from the pineal gland. Melatonin is an antioxidant,
antinociceptive, hypnotic, anticonvulsant, neuroprotective, anxiolytic, sedative and
analgesic. Melatonin is neurohormone with the profile of a novel hypnotic-anesthetic agent.
The purpose of this study is to investigate the preoperative, perioperative and
postoperative melatonin levels in bariatric surgery under general anesthesia and to
investigate the relationship between melatonin level and analgesia requirement.
Bariatric surgical procedures are associated with low short-term mortality and may be
associated with long-term reductions in all-cause, cardiovascular, and cancer-related
mortality. This surgeries are major surgeries include risk of mortality still.
Melatonin is a hormone secreted from the pineal gland. Melatonin is an antioxidant,
antinociceptive, hypnotic, anticonvulsant, neuroprotective, anxiolytic, sedative and
analgesic. Irregularity of melatonin secretion causes a sleep irregularities, psychosis in
intensive care unit and some behavioral disorder. The hypnotic, antinociceptive, and
anticonvulsant properties of melatonin endow this neurohormone with the profile of a novel
hypnotic-anesthetic agent.
The purpose of this study is to investigate the preoperative, perioperative and
postoperative melatonin levels in bariatric surgery under general anesthesia and to
investigate the relationship between melatonin level and analgesia requirement.
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