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Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma — Mel63; CHAMP  

Melanoma Clinical Trial

Official title:
A Trial to Evaluate the Immunogenicity and Safety of a Melanoma Helper Peptide Vaccine Plus Novel Adjuvant Combinations (MEL63)

Clinical Trial Summary

This study evaluates whether it is safe to administer a peptide vaccine in combination with different adjuvants. Adjuvants are substances that may boost immune responses vaccines. In this study, the adjuvants are Montanide ISA-51, polyICLC and cyclophosphamide. This study will also evaluate the effects of the combination of the peptide vaccine and the adjuvants on the immune system. The investigators will monitor these effects by performing tests in the laboratory on participants' blood, a lymph node, and tissue from the sites of vaccination.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02425306
Study type Interventional
Source University of Virginia
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date May 12, 2015
Completion date January 8, 2018
View Details
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