Melanoma Clinical Trial
Official title:
A Pilot Study of Neurocognitive Function in Patients Treated With Adjuvant Interferon Alpha-2b for High-Risk Melanoma
Interferon alpha is the only approved adjuvant biologic therapy for individuals diagnosed
with high risk malignant melanoma (stage 2 or 3). There is evidence that interferon has some
adverse cognitive effects on patients, but there are limited data. The investigators
hypothesis is that compared to patients with melanoma who do not receive interferon,
patients who have melanoma and are treated with interferon will show an objective decrease
in performance on neurocognitive assessment.
This study will enroll patients with melanoma who qualify for interferon, and either decide
to undergo interferon treatment or choose watchful waiting instead. All patients will be
assessed with a cognitive testing battery twice. Observation patients will undergo testing
at their first appointment in which they consent to the study, as well as at their next
physician visit, approximately 3 months from the first visit. Interferon patients will be
tested immediately prior to starting interferon, as well as immediately after completing
high dose interferon.
n/a
Observational Model: Case Control, Time Perspective: Prospective
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