Utility of Novel BRAF Test for Melanoma

Status Active, not recruiting

Clinical Trial Summary

This primary purpose of this study is to obtain blood samples from participants with both early and later stages of melanoma (Stage II/III and Stage IV). The researchers hope to better understand an abnormal protein found in many melanoma tumors called the BRAFV600 mutation. There will be two separate cohorts (groups) of participants on this study. You will be placed in one of the Groups. Group 1-For participants with advanced melanoma: Your existing tumor tissue sample will be compared to the blood samples given in order to further analyze and to understand the BRAFV600E gene mutation. Group 2-For participants with stage II/III melanoma: Following surgery, blood samples will be collected and analyzed. Understanding the BRAFV600E gene mutation in melanoma will help the researchers better understand the disease, and help plan treatment options for people with melanoma of all stages in the future.

Clinical Trial Description

There will be no extra clinic visits for this study. These research blood samples will be drawn at the same time as your regularly scheduled blood draws that are part of standard care for melanoma. About 2 to 4 teaspoons of blood will be drawn for each research sample. Depending on which group you are in, you will have either a one time blood draw or ongoing blood work for 1-2 years. ;

Study Design

Related Conditions & MeSH terms

Melanoma

Clinical Trial Details

NCT number	NCT01840527
Study type	Observational
Source	Massachusetts General Hospital
Contact
Status	Active, not recruiting
Phase
Start date	May 2013
Completion date	September 2022

View Details

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