Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1

Medication Administered in Error Clinical Trial

— DRP-EDiT  

Official title:

Right Place, Right Practitioner, Right Time: Development of Emergency Department Triage to Support the Identification and Management of Drug Related Problems

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05476705
• Other study ID #: IRAS 307523
• Status: Not yet recruiting
• Start date: April 2023
• Est. completion date: September 2023

Study information

• Verified date: July 2022
• Source: Anglia Ruskin University
• Contact: Daniel Greenwood
• Phone: 01245683082
• Email: daniel.greenwood[@]aru.ac.uk
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Up to a third of patients who visit emergency departments (EDs) do so because they have an issue with medicines prescribed by their doctor or purchased over the counter. For example, some patients might experience side effects (e.g., sickness), whereas others may feel their prescribed medicine is not working and want an alternative. While some patients who visit EDs know they have a problem with their medication, some are not aware. Furthermore, drug-related problems (DRPs) may not be identified by ED triage systems which are used to sort patients' priority for treatment. The currently used system in the UK (Manchester Triage System) mentions drugs infrequently and does not support the identification of the most common DRPs. For this project, DRPs include medication errors, adverse drug events, and adverse drug reactions. This project aims to revise the triage system to support the discovery of patients' medication problems when they are triaged by a nurse upon arrival to the ED. After identification, problems with a patient's medication should be dealt with by the healthcare professional who is most appropriate to manage that particular issue. For example, a patient who has been prescribed a new medicine but already takes 20 medicines will likely benefit from a review by a pharmacist in the ED. This project will aim to support the management of patients who might benefit from care provided by pharmacists by providing them with this care. As well as ensuring medication problems are identified at triage, and that pharmacists are involved in helping to deal with those problems, this project will also try to understand how we can investigate how pharmacists actually make a difference to the care of ED patients. A multi-step approach (Stages A-F) is proposed to answer the question "How can patient DRPs be identified, triaged and managed in the ED?" In summary, the steps include: STAGE A, a systematic review and scoping survey; STAGE B, researcher visits to ED sites to shadow ED staff; STAGE C, Interviews with healthcare professionals (including those shadowed in STAGE B) to validate findings of site visits and explore topics in more depth; STAGE D, developing additional drug-related content for the Manchester Triage System; STAGE E, involving a panel of experts in a RAND appropriateness method to rate the content developed in STAGE D; STAGE F, testing the revised triage system for a future pilot study involving interviews with staff visited in STAGE B.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 110
• Est. completion date: September 2023
• Est. primary completion date: September 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria: The following groups will be included in various stages of the project

• STAGE A: ED clinicians at UK-wide NHS trusts
• STAGE B: ED staff from 8 NHS sites across the UK
• STAGE C: ED staff from 8 NHS sites across the UK
• STAGE E: Clinicians and academics with expertise in Emergency Care and/or ED Triage
• STAGE F: ED staff from 8 NHS sites across the UK

Exclusion Criteria:

• Those who do not consent or who are unable to consent

Related Conditions & MeSH terms

• Drug-Related Side Effects and Adverse Reactions
• Medication Administered in Error
• Medication Reaction

Locations

Country	Name	City	State
n/a

Sponsors (4)

Lead Sponsor	Collaborator
Anglia Ruskin University	Ashford and St. Peter's Hospitals NHS Trust, Pharmacy Research UK, University of Manchester

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Suitability of a revised Manchester Triage System (MTS)	The suitability of a revised MTS to support identification and management of drug-related problems in the Emergency Department	13 months (the revised MTS will be an output from the analysis of data collected months 1 - 13)