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Medical Abortion clinical trials

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NCT ID: NCT05532085 Completed - Pain Clinical Trials

Assessment of Pain During an Abortion With Knowledge of the Predictive Factors of Pain.

Start date: June 12, 2020
Phase:
Study type: Observational

Two studies carried out in 2011 at the Center for Contraception and Voluntary Interruption of Pregnancy (CIVG) at the Louis-Mourier Hospital, evaluated the pain of patients undergoing an abortion, and looked for predictors of the pain felt during an abortion. medication or aspiration under local anesthesia. These predictive factors of pain are today integrated into the interview during a request for abortion at the CIVG of Louis-Mourier. This new study, on care data, prospective and monocentric conducted at the CIVG, of the Louis Mourier hospital, will make it possible to verify whether the knowledge of these predictive factors of pain has made it possible to improve the management of pain in women undergoing an abortion. The main objective is to assess the pain felt by the patient during a medical abortion or by aspiration under local anesthesia, knowing the predictive factors of pain highlighted by two studies carried out in 2011. The secondary objective is to highlight a significant difference in pain after application of an analgesic protocol indexed on predictive factors of pain. The study will be carried out in two successive periods: A first period of 4 months will consist in evaluating the pain felt by women having a medical abortion or by aspiration under local anesthesia. A second period of 4 months will evaluate the pain felt by women undergoing medical or aspiration abortion under local anesthesia following the application of an analgesic protocol indexed on the predictive factors of pain. The expected benefit of this study is the improvement of care and professional practices for better management of pain during outpatient abortion. The abortion will take place in the usual way according to the chosen method. An information and non-objection note will be distributed to patients during the first consultation for an abortion. Patients agreeing to participate in the study will answer the usual questions from the doctor or nurse. A data collection sheet related to care will be integrated into the medical records. The CIVG doctors taking part in the study will report the data collected on this form. The maximum pain felt during the abortion and in the following 4 days will be evaluated using an VAS according to usual practice.

NCT ID: NCT04181541 Completed - Medical Abortion Clinical Trials

Midlevel Versus Physician-provided Medical Abortion in the Second Trimester

Start date: February 17, 2020
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the safety and effectiveness of second trimester medical abortion when provided by nurse midwives compared with physicians. The study sample will be obtained from Michu Clinic, affiliated with St Paul's hospital, in Addis Ababa.

NCT ID: NCT03604341 Completed - Pain Clinical Trials

Cannabinoids for Pain Control During Medical Abortion

Start date: November 1, 2018
Phase: Phase 4
Study type: Interventional

The objective of this study is to determine if a synthetic cannabis derivative, dronabinol, in addition to ibuprofen, decreases maximum pain scores compared to ibuprofen and placebo in women undergoing medical abortion. Results of this study will help providers counsel patients regarding cannabis use during medical abortion.

NCT ID: NCT03148587 Completed - Medical Abortion Clinical Trials

Medical Abortion Self-Confirmation (MASC)

MASC
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

This study aims to investigate the ability of participants to perform and accurately interpret the multi-level pregnancy test and the low sensitivity pregnancy test following medication abortion, without routine provider contact.

NCT ID: NCT03014193 Completed - Medical Abortion Clinical Trials

Simplifying First Trimester Medical Abortion Follow-up

Start date: January 2017
Phase: N/A
Study type: Observational

This study evaluates the usability of the multilevel pregnancy test among women undergoing medical abortion.

NCT ID: NCT02985229 Completed - Medical Abortion Clinical Trials

Acceptability and Feasibility of Medical Abortion in Singapore

Start date: October 2016
Phase: Phase 3
Study type: Interventional

To test the hypothesis that a regimen of 200 mg oral mifepristone, with the option of home administration, followed by 800 μg buccal misoprostol 24 hours later for abortion through 70 days LMP will be feasible and acceptable in Singapore.

NCT ID: NCT02570204 Completed - Medical Abortion Clinical Trials

Self-Assessment of Medical Abortion Outcome Using Serial Multi-level Pregnancy Tests

Start date: September 2015
Phase: N/A
Study type: Interventional

This study aims to investigate the effectiveness and acceptability of the multi-level pregnancy test for self-assessment of abortion outcomes, without a routine provider contact.

NCT ID: NCT02343913 Completed - Medical Abortion Clinical Trials

Simplifying Menstrual Regulation (MR): Post Abortion Care in Pakistan

Start date: June 2014
Phase: N/A
Study type: Interventional

This study is an additional component of protocol 6005, titled Simplifying Menstrual Regulation (MR): Exploring the role of at-home semi-quantitative pregnancy tests for follow-up to menstrual regulation service provision in Pakistan. The study seeks to pilot a self-assessment checklist that will help women, who receive medical services for incomplete abortion, correctly identify warning signs and symptoms and determine whether to return to the clinic. The checklist can serve as a useful resource to help with the timely identification of women who need additional care and can help streamline service delivery. In addition, this study will provide important data on the role of misoprostol at varying levels of health services offering an array of treatments for incomplete abortion.

NCT ID: NCT02314754 Completed - Medical Abortion Clinical Trials

Outpatient Medical Abortion With Mifepristone and Misoprostol Through 77 Days of Gestation

XXGA
Start date: December 2014
Phase: Phase 4
Study type: Interventional

To demonstrate non-inferiority of the efficacy of 200 mg mifepristone followed in 24 to 48 hours by 800 µg buccal misoprostol in outpatient medical abortion services among women 71-77 days' compared to women 64-70 days' LMP.

NCT ID: NCT01920022 Completed - Medical Abortion Clinical Trials

Quickstart of Nexplanon® at Medical Abortion

Start date: October 2013
Phase: Phase 4
Study type: Interventional

Women having abortions are at high risk for subsequent unintended pregnancy and repeat abortion. Clearly, encouraging contraceptive use after abortion is a high priority. Long acting reversible contraceptives (LARCs, Implants and intrauterine contraception) are the most effective methods to help women avoid a repeat unwanted pregnancy and abortion. Studies in surgical abortion patients, show that "quickstart" of a LARC - i.e., inserting it during the surgical procedure - is associated with substantially greater use of that method six months later than requiring women to return later to get the device. However, today a majority of women chose medical abortion. The clinical routine is to insert LARCs at the follow up 2 to 3 weeks after the abortion treatment. Frequently women choose to do part of the abortion treatment at home and do not return for a follow up. Thus, the possibility to quick start a contraceptive method in medical abortion would be a major advantage especially if this could be done at the time of administration of mifepristone.