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Medical Abortion clinical trials

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NCT ID: NCT01150279 Completed - Medical Abortion Clinical Trials

Exploring the Role of At-home Semi-Quantitative Pregnancy Tests for Medical Abortion Follow-up

Start date: August 2009
Phase: Phase 2
Study type: Observational

This study will examine the feasibility, acceptability and usability of a semi-quantitative urine pregnancy test (dBest One Step hCG Panel Test Kit) for at-home follow-up after early medical abortion using mifepristone+misoprostol. The study seeks to: 1. Assess the feasibility of using this test in lieu of standard one-week clinic-based follow up for determination of complete abortion status as part of normal service delivery. In Mexico, follow up will be in two weeks, as is standard care in that . 2. To determine if women using this test at home understand how to use it and can correctly interpret the results; is it practical. 3. Assess women's and provider's acceptability of using at-home pregnancy tests in lieu of clinic-based follow up for confirmation of complete medical abortion in the future.

NCT ID: NCT00997347 Completed - Medical Abortion Clinical Trials

The Extended Gestational Age Medical Abortion Study

Start date: July 2009
Phase: Phase 4
Study type: Interventional

This open-label, comparative study will compare the efficacy, safety, and acceptability of 200 mg mifepristone followed in 24-48 hours by 800mcg buccal misoprostol or 400mcg sublingual misoprostol for termination of pregnancy in existing outpatient early medical abortion services among women 57-63 days' versus 64-70 days' gestation.

NCT ID: NCT00920465 Recruiting - Medical Abortion Clinical Trials

Treatment Regimens for Mifegyne and Cytotec

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to test two regimens of mifegyne and cytotec for medical abortion. The investigators hypothesize that administration of both medications during one hospital visit will not compromise effectiveness.

NCT ID: NCT00907725 Completed - Medical Abortion Clinical Trials

Does Follow-up With Serum Beta Human Chorionic Gonadotropin (BhCG) Simplify Medical Abortion?

Start date: May 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if BhCG testing to determine the completion of medical abortion simplifies the medical abortion protocol. Investigators hypothesize that women randomized to ultrasonographic determination of completion of medical abortion will have MORE follow-up visits/interventions beyond standard protocol than those randomized to medical abortion follow-up with serum BhCG. The investigators also hope to explore satisfaction with BhCG based follow-up among women seeking medical abortion. Investigators hypothesize that the majority of women who choose to follow-up with serum BhCG will be satisfied with this method of medical abortion follow-up.

NCT ID: NCT00621543 Completed - Medical Abortion Clinical Trials

Insertion of an Intrauterine Device (IUD) After Medical Abortion

Start date: March 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the expulsion and continuation rate of an intruterine device (IUD) placed immediately after medical abortion. Our hypothesis is that immediate-placement of an IUD after completed medical abortion will have a similar expulsion and continuation rate to traditional placement (4-6 weeks after pregnancy).

NCT ID: NCT00472394 Completed - Medical Abortion Clinical Trials

Determining Women's Preferences for Medical Abortion Using Willingness to Pay

Start date: October 2006
Phase: N/A
Study type: Observational

New medical abortion regimens are being tested with increasing frequency. However women's preferences for certain attributes of the regimes are not being investigated to any great degree. Consideration of women's preferences in designing new regimens may help to optimize the medical abortion process. The proposed prospective survey research will attempt to determine women's preferences for individual aspects of medical abortion treatment and various regimens, and to determine what attributes of medical abortion treatment may be driving these preferences. The information collected in this study may be used in developing future treatment regimens or as the groundwork for future research into preferences, acceptability, and satisfaction with treatment.

NCT ID: NCT00120224 Completed - Medical Abortion Clinical Trials

De-Medicalizing Mifepristone Medical Abortion

Start date: May 2005
Phase: N/A
Study type: Observational

This study will investigate the possibility that medical abortion using mifepristone and misoprostol - a safe, proven therapy for terminating early first trimester pregnancy - can be administered in a manner that is simpler and less costly than that routinely employed in the United States. The researchers hypothesize that: 1. Practitioners themselves, based on history and examination but without sonography, are able to dependably and correctly determine which patients are eligible for medical abortion and which patients either are not eligible or require further evaluation to determine eligibility. 2. Practitioners themselves, based on a symptom diary and low-sensitivity pregnancy test but without sonography, are able to dependably and correctly determine when a successful medical abortion has taken place and when referral for other possible outcomes should be made. 3. A symptom diary and low-sensitivity pregnancy test are safe and effective means of separating those women who could benefit from a follow-up visit from those who do not need one.