Clinical Trials Logo
  1. Home
  2. Meconium Aspiration Syndrome
  3. NCT06090981

Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome

Meconium Aspiration Syndrome Clinical Trial

Official title:
Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term (>=37 Weeks) Neonates With Actant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome: An Open Label Randomized Control Trial

Clinical Trial Summary

The objective of the study is to compare the total duration of respiratory support in term neonates (≥37weeks) with meconium aspiration syndrome, who are provided early(≤2hr) bolus surfactant therapy versus standard care.

Clinical Trial Description

Enrolled participants will be randomly assigned to one of two study groups: 1. early(≤2hr) bolus surfactant replacement therapy or 2. standard care Intervention group: The neonates enrolled in this group will receive early bolus surfactant replacement therapy within 2hr of life. Control group: The neonates enrolled in this group will receive standard care according to standard unit protocol ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06090981
Study type Interventional
Source Lady Hardinge Medical College
Contact Sushma Nangia, MD, DM
Phone +919810838181
Email drsnangia@gmail.com
Status Recruiting
Phase N/A
Start date March 12, 2022
Completion date March 12, 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT02041546 - Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Phase 4
Completed NCT04076189 - Time of Positive Pressure Ventilation in Non-vigorous Infants Born Through Meconium-stained Amniotic Fluid N/A
Not yet recruiting NCT02571231 - High Flow Ventilation With Volume Guarantee N/A
Completed NCT01758822 - Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies N/A
Completed NCT01328483 - Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome N/A
Withdrawn NCT03996317 - Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities N/A
Withdrawn NCT02708563 - Meconium Aspiration and Tracheal Suctioning—Feasibility Study N/A
Completed NCT01310621 - Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration Syndrome N/A
Recruiting NCT03346343 - Pulmonary Function Using Non-invasive Forced Oscillometry N/A
Completed NCT01757782 - Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns Phase 4
Completed NCT01274845 - Use of Heliox in the Management of Neonates With Meconium Aspiration Syndrome N/A
Recruiting NCT00312507 - Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration Phase 3