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Mechanical Insufflation-exsufflation and Hypertonic Saline in Nosocomial Bacterial Respiratory Tract Infection — ABSENTA  

Mechanical Ventilation Complication Clinical Trial

Official title:
Aspiration of Bronchial Secretions With Mechanical Insufflation-Exsufflation and Hypertonic Saline in Bacterial Nosocomial Tracheobronchitis and Pneumonia in Intubated Patients.

Clinical Trial Summary

Multicenter, randomized open label clinical trial to evaluate IEM and HS as concomitant therapy for respiratory tract infection in patients under artificial ventilation in the ICU. Lung infection is a serious complication that may occur during hospital stay and may need artificial respiration or even develop during artificial ventilation for other causes. Current specific treatment consists of intravenous antibiotics. The current study evaluated whether aspiration and drainage of infected sputum helps curing this severe complication and whether nebulized HS has additional benefits, like eradicating bacteria or reducing inflammation.

Clinical Trial Description

Open label randomized ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06310941
Study type Interventional
Source Hospital San Carlos, Madrid
Contact Miguel Sánchez Garcia, MD. PhD.
Phone +34658762739
Email miguelsanchez.hcsc@gmail.com
Status Not yet recruiting
Phase N/A
Start date December 1, 2024
Completion date December 30, 2026
View Details
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