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Mastitis clinical trials

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NCT ID: NCT05974956 Completed - Mastitis Clinical Trials

Effect of a Nursing Teaching Protocol on Mastitis Prognosis: Quasi-Experimental Research Design

Mastitis
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Aim: Evaluate the effect of a nursing teaching protocol on mastitis prognosis. Research design: Quasi-experimental research design was utilized. A convenient sample of sixty adult female patients diagnosed with mastitis, Patients divided equally into two groups(study and control) thirty for each.

NCT ID: NCT05409586 Completed - Clinical trials for Idiopathic Granulomatous Mastitis

Risk Factors and the Role of Albumin-to-globulin Ratio in Idiopathic Granulomatous Mastitis

Start date: April 20, 2022
Phase:
Study type: Observational

Albumin-to-globulin ratio (AGR) is an inflammation-based index that has been shown to have a role in many cancers and inflammatory diseases. Idiopathic granulomatous mastitis (IGM) is a rare inflammatory disease of the breast with a high recurrence rate. As a relatively new biomarker for inflammatory diseases, AGR's role in IGM recurrence has never been investigated in the literature. This study primarily investigates the possible risk factors for IGM recurrence and whether AGR can be used as a predictive factor.

NCT ID: NCT04596046 Completed - Clinical trials for Granulomatous Mastitis

Could Intralesional Steroid be the Novel Treatment for Granulomatous Mastitis?

IGM
Start date: November 19, 2019
Phase: N/A
Study type: Interventional

Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory breast disease that mimics malignancy owing to its features of appearance.In our research, we intended to compare the efficiency of local (intralesional) steroid administration with systemic (peroral) steroid. A total of 36 patients who had been histopathologically diagnosed with IGM and whose other factors had been microbiologically excluded were included in the study. The patients were randomized into two sub-groups that would be treated with systemic and local steroids. Of the patients, 19 were administered with 0.5-1 mg/kg/day peroral systemic steroid, and 17 were administered with 40-200 mg/ml intralesional local steroid regarding the severity of the lesion. All patients were evaluated through physical examination one week after the completion of the treatment. Subsequently, the follow-up of the patients was performed thorough physical examination and ultrasonography and/or magnetic resonance imaging at the 1st, 3rd, and 6th months.

NCT ID: NCT04543149 Completed - Clinical trials for Granulomatous Mastitis

Immune Cells in Patients With Granulomatous Mastitis

Start date: August 1, 2020
Phase:
Study type: Observational

Granulomatous mastitis is a rare, chronic, benign inflammatory disease of the breast that plays a role in many varying etiologies, including infectious and non-infectious causes. Etiological reasons were examined in various studies, but neither etiology nor definite criteria for diagnosis were found. Our aim in this study is to examine the role of immunophenotyping in differentiating the etiology of granulomatous mastitis and using it as a prognostic marker.

NCT ID: NCT04540237 Completed - Clinical trials for Granulomatous Mastitis

Serum Cytokine Values in Patients With Granulomatous Mastitis

Start date: September 1, 2020
Phase:
Study type: Observational

Granulomatous mastitis is a rare, chronic, benign inflammatory disease of the breast that plays a role in many varying etiologies, including infectious and non-infectious causes. Etiological reasons were examined in various studies, but neither etiology nor definite criteria for diagnosis were found. Our aim in this study is to examine the role of cytokines in differentiating the etiology of granulomatous mastitis and using it as a prognostic marker.

NCT ID: NCT03724903 Completed - Clinical trials for Granulomatous Mastitis

Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

A single-arm, proof-of-concept trial has shown the safety and efficacy of ductal lavage as a treatment for idiopathic granulomatous mastitis patients (Manuscript accepted in Journal of Surgical Research 2018). In this multicenter, randomized, open-labeled, non-inferior trial, the investigators are going to enroll eligible granulomatous mastitis patients and randomized them into ductal lavage versus. corticosteroids therapy group. The primary endpoint of this study is the complete clinical response rate at 1 year after the enrollment. The aim of this study is to provide evidence for the management of idiopathic granulomatous mastitis patients .

NCT ID: NCT02794688 Completed - Mastitis Clinical Trials

Ductal Lavage in Non-lactating Female Women With Mastitis

Start date: August 2016
Phase:
Study type: Observational

RATIONALE and PURPOSE: For non-lactational mastitis patients pathologically diagnosis of idiopathic granulomatous mastitis (IGM) or periductal mastitis (PD), the investigators hypothesized that ductal lavage is able to relieve the symptoms and achieve complete response, with shorter recovery time than oral intake of antibiotics or corticosteroids treatments. This single arm, observational, case series, pilot study is going to evaluate the effectiveness of ductal lavage in patients with non-lactational IGM or PD.

NCT ID: NCT02755012 Completed - Infection Clinical Trials

Impact of Maternal Stress on Infant Stunting

Start date: June 2012
Phase: N/A
Study type: Observational

This study takes place in rural Mam-Mayan communities of Guatemala characterized by high rates of childhood stunting. It aims to characterize women's exposure to nutrition, infection and psychosocial stressors vs. resilience factors, to evaluate the cumulative impact of maternal-level factors (nutritional, infectious, psychosocial), social factors (autonomy, social support, domestic violence), and household factors (socioeconomic status, food security) on early infant growth, and to evaluate whether maternal cortisol may be a mediator in the vertical transmission of stress.

NCT ID: NCT02667132 Completed - Clinical trials for Granulomatous, Mastitis

Granulomatous Mastitis Current Approach and Treatment

Start date: December 2015
Phase: N/A
Study type: Observational

The aim of this study was to retrospectively review the granulomatous mastitis and evaluated current approach and treatment. HYPOTHESIS Although there is no common protocol for the treatment and management process of GM, the ternary treatment (medical treatment following by surgical procedure, Steroid+Antibiotic and surgical procedure, respectively) is considered as the most successful treatment approach.

NCT ID: NCT02203877 Completed - Mastitis Clinical Trials

Evaluation of Lactobacillus Fermentum CECT5716 on the Incidence of Mastitis

Start date: August 2013
Phase: N/A
Study type: Interventional

To evaluate the effect of the consumption of Lactobacillus fermentum CECT5716 on mastitis incidence.