Mapping the Lumbar Spine Marrow Adiposity

Marrow Adiposity Lumbar Spine Clinical Trial

— FATFRAC  

Official title:

Mapping the Lumbar Spine Marrow Adiposity

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02887716
• Other study ID #: FATFRAC
• Status: Completed
• Phase: N/A
• First received: August 30, 2016
• Last updated: August 30, 2016
• Start date: August 2015
• Est. completion date: November 2015

Study information

• Verified date: August 2016
• Source: University Hospital, Brest
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: The Commission nationale de l’informatique et des libertés
• Study type: Observational

Clinical Trial Summary

The objective of this study is to describe the change in the percentage of fat in the lumbar spine.

Description:

The study of the distribution of bone marrow adiposity is little known in subjects who did not have pathology likely to alter the fat content of the vertebrae. Or that fat content is potentially a reflection of brittle bones (osteoporosis, for example), and deserves to be known because it can be used to normalize the lipid fraction values with respect to age or from the level (L1 , L2, L3, L4 or L5) of the vertebra being studied.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: November 2015
• Est. primary completion date: November 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Consecutive patients who underwent MRI of the lumbar spine with Sagittal sequenceT1, T2 STIR and IDEAL, good quality, in a clinical setting type back pain, spondylitis research, radicular syndrome ...

• Examinations conducted between 2014 and 2015 on the same equipment

• Major patient

• Having formulated their non-opposition

Exclusion Criteria:

• Previous history of neoplastic disease

• Vertebral Fracture

• Pathology reaching the vertebral body detectable by MRI (disc lesion with rearrangements of the endplates (MODIC)

• Inflammation,

• Bone tumor,

• fracture

• Refusal of participation

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Marrow Adiposity Lumbar Spine
• Obesity

Locations

Country	Name	City	State
France	CHRU de Brest	Brest

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Brest

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Value of the fat fraction by vertebral level of the lumbar spine, in MRI, measured on the mapping generated by the IDEAL-IQ sequence.		3 months	No