Periodontally Accelerated Osteogenic Orthodontics With BMP2

Status Completed

Clinical Trial Summary

rhBMP-2 has the potential to function as a regenerative material in periodontally accelerated osteogenic orthodontics (PAOO). This study aimed to assess the effects of PAOO with BMP-2 on outcomes such as treatment period, bone density, healing and pain.

Clinical Trial Description

Subjects were randomly assigned into each of the following experimental groups; C+BMP: corticotomy with 0.5 μg/mL rhBMP-2 and C: corticotomy only. Clinical parameters included recording the duration of treatment period, visual analogue scale (VAS) scores and early healing index (EHI) scores. The evaluation of bone density was performed at baseline, 3 months and 6 months by using RVG. ;

Study Design

Related Conditions & MeSH terms

Malocclusion

Clinical Trial Details

NCT number	NCT03396900
Study type	Interventional
Source	SVS Institute of Dental Sciences
Contact
Status	Completed
Phase	Phase 2
Start date	July 1, 2016
Completion date	November 1, 2017

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