Malocclusion Clinical Trial
Official title:
Alveolar Microperforation for Inflammation-Enhanced Tooth Movement During Orthodontic Treatment
The purpose of this research study is to assess the clinical effectiveness of the procedure of a minimally invasive alveolar microperforation procedure to achieve accelerated tooth movement in patients undergoing orthodontic treatment. "Accelerated tooth movement" means that using the PROPEL™ device may help complete your treatment with braces on one side of your mouth sooner than would be expected if the device were not to be used.
Following informed consent and satisfying the screening/enrollment assessments, a panoramic
and periapical radiograph of the teeth designated for micro-osteoperforation treatment is to
be taken. Prior to the intervention the subjects will swish 5cc of chlorhexidine for one
minute, twice. Micro-osteoperforation, PROPEL™, is conducted under local or topical
anesthesia AFTER the subject is banded and bonded. The procedure will be randomized to
either the left or right side in each subject. Following the procedure, Chlorhexidine rinses
are to begin twice a day for a week.
The subjects will be advised to take Tylenol only in case of significant pain. Subjects will
be seen four to six weeks after completion of treatment for the first follow-up. Subjects
will be followed up with a telephone consult 24 hours after micro-osteoperforation is
performed. They will be asked if any pain medication was taken after being dismissed from
the research center and if so, they will be asked the name and dose of medication taken.
Study will conclude at the 6 month follow up visit or when space on the treating side is
closed.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02914431 -
Personalized Titanium Plates vs CAD/CAM Surgical Splints in Maxillary Repositioning of Orthognathic Surgery
|
N/A | |
| Recruiting |
NCT05383820 -
Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment
|
Phase 4 | |
| Not yet recruiting |
NCT03794726 -
Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery
|
N/A | |
| Not yet recruiting |
NCT03513003 -
The Use of a Pacifier to Correct Malocclusions in Young Children
|
N/A | |
| Completed |
NCT02603289 -
One Week Aligner Evaluation
|
||
| Terminated |
NCT01210547 -
Three-dimensional Assessment of Craniofacial Structures
|
N/A | |
| Completed |
NCT01463839 -
Sleep Disorder and Oral Habits in Children
|
N/A | |
| Recruiting |
NCT04946201 -
Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
|
||
| Recruiting |
NCT04117360 -
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
|
||
| Active, not recruiting |
NCT06291129 -
Gingival Health and Malocclusion Among Type 1 Diabetic Children and Adolescents
|
N/A | |
| Recruiting |
NCT05684510 -
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
|
N/A | |
| Completed |
NCT02659813 -
Orthodontic Archwire Effectiveness Trial
|
N/A | |
| Completed |
NCT02427763 -
Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
|
Phase 0 | |
| Completed |
NCT01962012 -
Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
|
Phase 4 | |
| Completed |
NCT02267811 -
The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement
|
N/A | |
| Completed |
NCT03405961 -
A Comparison of Conventional Versus Digital PAR (Peer Assessment Rating) Scores Using an Intraoral Scanner
|
||
| Completed |
NCT05356780 -
Predictability of Orthodontic Tooth Movement With Invisalign Aligners
|
||
| Recruiting |
NCT06218641 -
Discomfort Perceived by a Cohort of Patients Treated With Aligners and Attachments Placed According to Two Different Protocols
|
N/A | |
| Completed |
NCT05711160 -
Comparison of the Accuracy and Reliability of Measurements Made on CBCT and IOS Images With Their made-on Plaster Models.
|
||
| Recruiting |
NCT06140043 -
Augmented Reality for Orthognatic Surgery Patient Education
|
Phase 2/Phase 3 |