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Malocclusion clinical trials

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NCT ID: NCT02411812 Recruiting - Clinical trials for Malocclusion, Angle Class II

Effects of the Herbst Appliance With Different Anchorages and Twin-Block Appliance in Class II Malocclusion

HASA
Start date: August 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the Herbst appliance with indirect skeletal anchorage in mini-implants is capable of preventing excessive inclination of the lower incisors at the end of the treatment when compared to the Herbst appliance with dental anchorage and Twin-Block appliances in patients with Class II malocclusion and overjet ≥ 6 mm.

NCT ID: NCT02376829 Completed - Malocclusion Clinical Trials

Class II Correction Study Using the Invisalign System

Start date: March 2015
Phase: N/A
Study type: Interventional

To demonstrate that growing teenagers which present up to full cusp Class II malocclusions can be treated using the Invisalign System.

NCT ID: NCT02359760 Completed - Malocclusion Clinical Trials

Assessment of Piezoelectric Periodontal Surgery Effects on Orthodontic Treatment: a Prospective Pilot Study

Start date: March 2015
Phase: N/A
Study type: Interventional

INTRODUCTION: Dentoalveolar surgeries such as piezocision, have been developed with the aim to accelerate the tooth movement and therefore reduce the length of orthodontic treatment. Although this surgical technique seems to present several advantages, such as decreased risk of decalcification or orthodontic relapse, its use as a routine practice is not yet recommended. The main purpose of this study is to determine the duration of orthodontic treatment by using the piezocision. The secondary objectives are to evaluate the effect of this surgical technique on bone density, root resorption, osteoclast activity, inflammatory events and pain assessment. MATERIAL AND METHODS: The investigators will conduct a prospective study. The experimental group will consist of 14 adults, subjects from 18 to 40 years-old (10 women, 4 men). The control group will consist of 30 matched patients, who have been already treated in the orthodontic clinic of the University of Montreal. The reliabilities of Intra and Inter assesors will be measured for each doctor. After completion of the surgical guides from CBCT, the Piezocision will be performed the same day of the bracket indirect placement. The surgical procedure will be standardized and did it by the same surgeon. The appointments will be every 2 weeks for 4 months, then every month. The investigators will make an assessment of pain by using a numerical visual scale, during the first 7 days after surgery. Analysis of inflammatory markers (IL-1) and osteoclast activity (RANKL, OPG) will be evaluated from the gingival sulcus fluid collected at day 0, 1, 3, 5, 8, 12, 16 and 24 weeks. At the end of the treatment, the overall quality evaluation of treatment using the "American Board of Orthodontics' grading system" would be realized by two blind external observers to limit bias.

NCT ID: NCT02357771 Completed - Malocclusion Clinical Trials

Probiotic Lozenge Reduce Streptococcus Mutans in Plaque in Orthodontic Bracket Patients

Start date: April 2015
Phase: Phase 3
Study type: Interventional

Advances in orthodontics have improved the quality of appliances and treatment protocols, raising the standard of patient care. However, enamel demineralization is still a problem associated with orthodontic treatment, leading to the formation of white spot lesions; this is a grave concern to orthodontists and patients. The overall prevalence of white spot lesions among orthodontic patients has been reported to be between 4.9% and 84%.1 When basic oral hygiene is poor, orthodontic appliances create areas of plaque stagnation, especially around brackets, bands, wires, and other attachments. Levels of acidogenic bacteria, present in the plaque, notably Streptococcus mutans (S mutans), are higher in orthodontic patients than in non-orthodontic patients. This causes demineralization around the brackets and leads to white spot lesions. They are most prevalent around the cervical region of bands in the posterior region, whereas in the anterior region, the lateral incisors in both arches, followed by the canines, are most commonly affected.

NCT ID: NCT02311491 Withdrawn - Malocclusion Clinical Trials

Nano-Crystalline Ceramic Coating of Orthodontic Archwires

Start date: December 2016
Phase: N/A
Study type: Interventional

Purpose: The project aims to assess if hard ceramic coatings on orthodontic archwires will reduce the sliding resistance of archwires in the brackets during orthodontic treatment procedures. Participants: Up to 80 subjects will be recruited for this study. Subjects between 10 years of age and 45 years old will be otherwise healthy subjects previously diagnosed with malocclusion. Procedures (methods): Each subject will receive an experimental (coated) or a regular (uncoated control) orthodontic archwire (AW) for a 3-month treatment. The 3D digital images of each subject's dentition will be recorded three times at 0-, 6- and 12-week visits. The AW will be removed and retrieved after the 3-month trial.

NCT ID: NCT02290158 Completed - Malocclusion Clinical Trials

Effects of a Finishing Protocol Implementation in Orthodontic Patients

Start date: June 2013
Phase: N/A
Study type: Interventional

This study evaluates the effects of a finishing protocol in orthodontic outcomes using ABO-OGS scores. Patients who finish orthodontic treatment and fulfill the inclusion and exclusion criteria receive a treatment using a finishing protocol and their scores are compare with 40 patients who don't receive a finishing protocol

NCT ID: NCT02267850 Completed - Malocclusion Clinical Trials

Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time

Start date: May 2013
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on orthodontic treatment time. This is a double-blinded RCT with half the patients receiving treatment from a sham non-functional device, serving as controls, and the other half receiving light therapy treatment from a functional OrthoPulse™. Orthodontic treatment time for the sham-control patients are compared to that of the OrthoPulse™ patients.

NCT ID: NCT02267837 Completed - Malocclusion Clinical Trials

OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study

Start date: December 2012
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on the rate of anterior orthodontic alignment.

NCT ID: NCT02267824 Completed - Malocclusion Clinical Trials

The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment

Start date: December 2010
Phase: N/A
Study type: Interventional

The aim of this study is to determine if extraoral OrthoPulse®, which emits extraoral LED (Light Emitting Diode) photobiomodulation (PBM), reduces the time it takes to complete orthodontic alignment.

NCT ID: NCT02267811 Completed - Malocclusion Clinical Trials

The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement

BX8RN
Start date: October 2013
Phase: N/A
Study type: Interventional

This open label study is designed to evaluate the ability of OrthoPulse™ to safely and effectively increase the rate of orthodontic tooth movement with fixed appliances.