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Malocclusion clinical trials

View clinical trials related to Malocclusion.

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NCT ID: NCT04316403 Completed - Clinical trials for Class II Division 1 Malocclusion

Laser-assisted Flapless Corticotomy in Accelerating Canine Retraction

Start date: February 15, 2015
Phase: N/A
Study type: Interventional

Erbium lasers have been suggested to accomplish corticotomy without flap reflection due to their attractive advantages. The current trial aimed to evaluate the efficacy of laser-assisted flapless corticotomy in accelerating orthodontic tooth movement. The secondary aim was to evaluate the patients' responses to laser application. It was postulated that canine retraction after laser-assisted flapless corticotomy would be accomplished within a shorter period compared with the conventional canine retraction method, with no significant degree of pain and discomfort.

NCT ID: NCT04310267 Completed - Clinical trials for Skeletal Class 3 Malocclusion Due to Maxillary Deficiency

Three Levels of Force Application for Maxillary Protraction

MaxiProtr
Start date: June 5, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate dentoskeletal changes concomitant with different three levels of force application for maxillary protraction in growing patients with skeletal class 3 malocclusion.

NCT ID: NCT04276402 Completed - Clinical trials for Malocclusion, Angle Class II

Effect of Photobiomodulation by 808nm Diode Laser on the Stability of Orthodontic Mini-implants.

Start date: July 5, 2019
Phase: N/A
Study type: Interventional

The study aimed to evaluate the influence of a 635nm diode laser on the stability of orthodontic mini-implants in vitro, as well as mini-implants failure rate (mini-implant loss) and patients pain level after the treatment. A randomized clinical split-mouth trial was concluded with 22 subjects (14 women, 8 men), 44 orthodontic mini-implants with a diameter 1.4mm and length of 10mm. Mini-implants were placed between teeth 3 and 4; and 13 and 14 (Universal Numbering System), in the area of the attached gingiva, 2 mm below mucogingival junction.

NCT ID: NCT04266769 Completed - Dental Malocclusion Clinical Trials

Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency

Start date: February 10, 2020
Phase: N/A
Study type: Interventional

This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.

NCT ID: NCT04255511 Completed - Clinical trials for Mandibular Retrognathism

Effects of Orthopedic Mandibular Advancement in Class II Division 1 Malocclusion on Pharyngeal Airway

Start date: December 10, 2019
Phase: N/A
Study type: Interventional

This study aims at evaluating the effects of mandibular advancement on pharyngeal airway space and nocturnal breathing in children with skeletal class II division1 malocclusion. Fifty patients will be enrolled in the study divided into control and experimental groups.

NCT ID: NCT04225637 Completed - Malocclusion Clinical Trials

Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol. The purpose of the clinical trial is to evaluate and compare the effects of slow and rapid activation rates of miniscrew-supported expanders on the skeletal changes, dento-alveolar changes and the pain experience.

NCT ID: NCT04202016 Completed - Clinical trials for Class II Div 1 Malocclusion

The Rate of Space Closure With Piezocision-based Corticotomy in Different Facial Types: A Split-mouth Design

RCT
Start date: November 1, 2018
Phase: N/A
Study type: Interventional

23 female participants with class II div I will have extraction of bilateral first bicuspids 10 weeks after bond- up appointment. The extracted teeth will be preserved in special containers for subsequent microscopic analysis. Four months later, upon space closure phase, the patient will have a piezocision surgery on one side randomly chosen. Virtual models will be generated once before the surgery and monthly after for four and a half months. The models will be scanned by CADCAM and later tooth movement will be analyzed in regards to the rugae area.

NCT ID: NCT04175405 Completed - Clinical trials for Malocclusion, Angle Class II

Low-level Laser Therapy With a 635nm Diode Laser on Orthodontic Mini-implants Stability.

Start date: March 6, 2019
Phase: N/A
Study type: Interventional

The study aimed to clinically estimate an influence of a 635nm diode laser on the primary and secondary stability of orthodontic mini-implants placed in a maxilla, to assess mini-implants failure rate (mini-implant loss) and to evaluate a pain level after the treatment. The randomized clinical split-mouth trial included 15 subjects, 30 implants (Dual Top Anchor System, Seoul, Korea) with a diameter 1.4mm and length of 10mm. Mini-implants were placed in the area of the attached gingiva between the second premolar and first molar teeth 2 mm below the mucogingival junction of both sides of the maxilla in 20 patients (13 women and 7 men; age: 32.5 ± 6.1 years).

NCT ID: NCT04170127 Completed - Clinical trials for Malocclusion, Angle Class II

Photobiomodulation of Orthodontic Mini-implants by a 635nm Diode Laser

Start date: February 2, 2019
Phase: N/A
Study type: Interventional

The study aimed to estimate clinically an influence of 635nm diode laser on the primary and secondary stability of orthodontic mini-implants placed in a maxilla, to assess mini-implants failure rate (mini-implant loss) and to evaluate a pain level after the treatment. The randomized clinical split-mouth trial included 15 subjects, 30 implants (Dual Top Anchor System, Seoul, Korea) with a diameter 1.4mm and length of 10mm. Mini-implants were placed in the area of the attached gingiva between the second premolar and first molar teeth 2 mm below the mucogingival junction of both sides of the maxilla in 15 patients.

NCT ID: NCT04070001 Completed - Crowding, Tooth Clinical Trials

The Effects of Ibuprofen and Laser on Orthodontic Pain

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Early orthodontic pain is usually caused by the insertion of elastomeric separators to the mesial and distal of the tooth to be banded in order to create adequate space for proper placement. Recent studies have demonstrated that the pain reaches its peak at 24 hours and then gradually decreases within 7 days The intensity of this pain is sometimes perceived as extremely high to cause a significant number of patients to discontinue the treatment. Nonsteroidal anti-inflammatory drugs, which block the prostaglandin synthesis through inhibiting the cyclooxygenase activity, is one of the most common methods used to manage the orthodontic pain. It has been reported that these drugs decrease the orthodontic tooth movement rate, in addition to many systemic side effects such as gastric and duodenal ulceration, coagulation disorders, congestive heart problems and allergic effect. The application of low-level laser therapy (LLLT) also reported being efficient in accelerating orthodontic tooth movement and in alleviating orthodontic pain without any apparent side effects. LLLT is thought to reduce the pain by increasing the local blood flow, inhibiting the secretion of inflammatory substances, inducing the release of neurotransmitters, altering the conduction and excitation of peripheral nerves and stimulating the endorphins release. On the other hand, literature review on the effectiveness of LLLT in alleviating orthodontic pain observed after elastomeric separator placement (ESP) exhibited conflicting results. While LLLT was found to be effective in some studies, the others refuted its effectiveness. When studies on alleviating orthodontic pain observed after ESP were reviewed, it was determined that the effects of many drugs and LLLT were evaluated subjectively by VAS. Furthermore, only in one study, the effects of ibuprofen and LLLT were compared using PGE2 levels in GCF and VAS. Based on that, this study was aimed to compare the effects of ibuprofen and LLLT in alleviating orthodontic pain observed after ESP through IL-1β and SP levels in GCF and VAS.