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Malnutrition clinical trials

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NCT ID: NCT02257762 Active, not recruiting - Child Malnutrition Clinical Trials

Efficacy of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this trial is to evaluate the efficacy of the LNS on children aged 6-17 months in preventing growth faltering and improving micronutrient status. The impact of product will be compared to Corn Soy Blend ++ (CSB++), Sprinkles, and to a control group consuming an unsupplemented diet, which is usually borbor at an early age, and thereafter, family foods.

NCT ID: NCT02102659 Active, not recruiting - Malnutrition Clinical Trials

Biological Assessment of Clinical Nutrition and Its Application

Start date: March 2014
Phase: N/A
Study type: Interventional

1. Clinical nutritional support therapy is an important progress of modern medicine. 2. Conventional methods of clinical nutrition assessment (Anthropometric, lab, etc.) not just lack of accuracy and immediacy but also difficult to dynamically reflect the fluctuation trend of nutrition status. 3. It has been reported that malnutrition affects proliferation and apoptosis of human cells in vivo. This preliminary study was initiated by the hypothesis that changes in nutritional status may be reflected rapidly in fast proliferating cells. 4. In the previous studies the investigators already found that apoptosis rate of oral mucosal epithelium could reflect changes in nutritional status.There were an obvious decreasing in apoptosis and proliferation rate of oral mucosal epithelium in malnourished patients. 5. Based on the patient's curve of apoptosis rate of oral mucosal epithelium, the plateau being achieved by increase the nutrition amount continuously, Maintain this amount of nutrition given until the end of treatment. The investigators call this amount of nutrition the "upper limit nutrition support therapy". 6. The patients applying for"upper limit nutrition support therapy" and "Formula nutrition support therapy" separately, comparing of the two methods influences on postoperative wound healing, postoperative complication rate ,inflammatory response, side effects of chemotherapy, hospital stays and hospitalization expenses.

NCT ID: NCT01804855 Active, not recruiting - Obesity Clinical Trials

Effectiveness of a Smartphone App for Adolescent Obesity Management

Start date: February 2013
Phase: N/A
Study type: Interventional

Though face-to-face treatment of childhood obesity can be effective, it is time consuming and costly. This study will test whether treatment can be delivered via an Android app and whether such treatment reduces obesity.

NCT ID: NCT01775150 Active, not recruiting - Malnutrition Clinical Trials

Saving Mother and Baby With Text Messaging

Start date: October 2011
Phase: N/A
Study type: Interventional

We plan to integrate WHO educational material using mobile phone text messaging, target on pregnant women in remote rural areas in China. We hypothsized that text messaging can have major impact on reducing maternal and infant deaths in rural China because text messaging is accessible, acceptable, and affordable.

NCT ID: NCT01590095 Active, not recruiting - Malnutrition Clinical Trials

WASH Benefits Bangladesh

Start date: May 2012
Phase: N/A
Study type: Interventional

Brief Summary: The purpose of this study is to measure the independent and combined effects of interventions that improve water quality, sanitation, hand washing, and nutrition on child growth and development in the first years of life.

NCT ID: NCT01303016 Active, not recruiting - Malnutrition Clinical Trials

Improving Nutrition and Health Outcomes in Intibuca, Honduras

MANI II
Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this research study is to better understand how to prevent malnutrition in children under age 5 years in Intibuca, Honduras. A randomized community trial design was used to implement a nutrition program, including a complementary nutrition supplement, educational sessions, and growth and health monitoring integrated into the basic primary care package, to participants living in communities in the intervention group. Participants living in the control group communities will receive the nutrition supplement for one year following the study.

NCT ID: NCT01239693 Active, not recruiting - Infant Malnutrition Clinical Trials

Supplementing Maternal and Infant Diet With High-energy, Micronutrient Fortified Lipid-based Nutrient Supplements (LNS)

iLiNS-DYAD-M
Start date: February 2011
Phase: Phase 3
Study type: Interventional

The use of lipid-based nutrients (LNS), such as Nutributter or fortified spread (FS), have been associated with improved growth and development outcomes among infants in Ghana and Malawi. Modified versions of such supplements have been developed to improve their nutrient density and quality and to lower their costs. Such modified products have proven acceptable to pregnant women in Malawi and Ghana. In the present trial, the investigators aim to test the effect of LNS on pregnancy and child outcomes, when given during pregnant and lactating women and their infants from 6 to 18 months of age. In control groups, participants will receive either iron+folate tables during pregnancy only or multiple micronutrient tablets during pregnancy and first six months of lactations. The main hypothesis to be tested suggests that the mean length-for-age Z-score (LAZ) of 18-month-old infants who received LNS between 6 and 18 months of age and whose mothers were provided with LNS during pregnancy and the first 6 months of lactation is higher than the mean LAZ score of same age infants who received no dietary supplements and whose mothers received iron-folate supplementation during pregnancy only. To detect the long-term effect of the LNS supplementation, we now propose to conduct a follow-up study when the children are 9 years old, to see if the intervention had effect on children's growth, cardiometabolic and respiratory status and neurocognitive development.

NCT ID: NCT01141166 Active, not recruiting - Malnutrition Clinical Trials

Octabaix Intervention Study

Start date: January 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Objective: To determine the effectiveness of an individual multifactorial intervention on falls and undernutrition risk in very older people in the community.

NCT ID: NCT00309426 Active, not recruiting - Malnutrition Clinical Trials

Effect of Fetuin A in Hemodialysis Patients

Start date: March 2001
Phase: N/A
Study type: Observational

The purpose of this study is to examined the effect of fetuin A on atherosclerosis and prognosis in hemodialysis patients.

NCT ID: NCT00131417 Active, not recruiting - Malnutrition Clinical Trials

Ready to Use Therapeutic Food in the Rehabilitation of Severely Malnourished Children

Start date: October 2004
Phase: Phase 3
Study type: Interventional

Severe malnutrition is a major cause of child morbidity and mortality in developing countries especially sub-Saharan Africa. The hospital mortality rate due to severe malnutrition in developing countries ranges from 20-30%. For the rehabilitation of severely malnourished children, the World Health Organization (WHO) recommends a liquid milk-based diet, Formula 100 (F100), which contains 100 kilocalories per 100 milliliters. In Uganda, the rehabilitation of severely malnourished children is based on High Energy Milk (HEM), which is reconstituted cows milk with a nutritional composition similar to F100. Recently a semi-solid ready-to-use therapeutic food (RUTF) with similar composition as F100 or HEM has been designed. This preparation can be eaten without adding water hence reducing the risk of bacterial contamination. The preparation can be used at home with minimal supervision. Hitherto the efficacy of RUTF in the rehabilitation of severely malnourished children in Uganda has not been studied. The purpose of this study is to determine whether giving daily RUTF in the rehabilitation of severely malnourished children will result in a higher weight gain than giving HEM.