Questionnaires in Assessing Attitudes About Legalization of Marijuana Use in Participants With Cancer

Malignant Neoplasm Clinical Trial

Official title:

A Comparison of the Attitudes About Legalization of Marijuana Use for Medical Purposes by Cancer Patients in Two Cancer Centers Located in a Legalized and a Non-Legalized State

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03360799
• Other study ID #: 2017-0568
• Secondary ID: NCI-2018-0102620
• Status: Completed
• Start date: November 17, 2017
• Est. completion date: August 26, 2019

Study information

• Verified date: August 2019
• Source: M.D. Anderson Cancer Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This trial studies attitudes about legalization of marijuana use in participants with cancer. Questionnaires may help doctors to learn about and compare the attitudes that patients in non-legalized and legalized states have towards the legalization of medical marijuana.

Description:

PRIMARY OBJECTIVES:

I. To compare the proportion of cancer patients' who have a positive attitude about legalizing marijuana for medical purposes between those in a legalized versus (vs.) a non-legalized state.

SECONDARY OBJECTIVES:

I. To evaluate the association of cancer patients' belief in the usefulness of medical marijuana in their state of residency (Texas versus Arizona).

II. To examine the association of demographic, physical and psychosocial characteristics of patients and their perception of medical marijuana.

III. To examine the preference of patients for treatment of pain, anxiety and depression between medical marijuana vs. opioids, anti-anxiety and anti-depressant medications.

IV. To examine the association of media to perception of use of medical marijuana.

V. To evaluate the association of cancer patients' attitude about legalizing marijuana for medical purposes vs. recreational purposes.

VI. To examine the association of patients who have used marijuana for certain medical conditions/symptoms and their belief of how it has affected that condition/symptom.

VII. To compare demographic, physical and psychosocial characteristics of patients who have used marijuana for medical purposes.

VIII. To compare demographic, physical and psychosocial characteristics of patients who have used marijuana for non-medical purposes. IX. To compare demographic, physical and psychosocial characteristics of patients who believe marijuana is useful for medical reasons.

OUTLINE:

Participants complete 5 questionnaires.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 103
• Est. completion date: August 26, 2019
• Est. primary completion date: August 26, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients (inpatient or outpatient) seen by the Palliative Care team at Banner MD Anderson or UT MD Anderson

• Patients able to speak and read English

• Patients enrolled in each site must be a resident of the state where that site is located (e.g. if a patient is enrolled at UT MD Anderson Cancer Center [MDACC], they should be resident of the state of Texas)

• Patients should have a cancer diagnosis

Exclusion Criteria:

• Patients who are not able to speak or read English

• Altered mental status as determined by the interviewer based on the ability to understand the nature of the study and consent process

Related Conditions & MeSH terms

• Malignant Neoplasm
• Marijuana Use
• Neoplasms

Intervention

Other:
• Questionnaire Administration
Complete questionnaires

Locations

Country	Name	City	State
United States	Banner MD Anderson Cancer Center	Gilbert	Arizona
United States	M D Anderson Cancer Center	Houston	Texas

Sponsors (2)

Lead Sponsor	Collaborator
M.D. Anderson Cancer Center	National Cancer Institute (NCI)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Positive attitude regarding the legalization of medical marijuana for medical purposes	Will be defined as answering "Completely Agree" or "Slightly Agree" to the question 1 in Marijuana Survey for Patients. The number of subjects with positive attitude towards legalizing medical marijuana will be compared between patients from Texas and Arizona States using one-sided Fisher's exact test or chi-squared test, whichever appropriate. A logistic model will be used to assess the effect of state of residency, adjusting for other covariates such as gender, age, race, etc. Will employ inverse probability of state weighting using the propensity score on all patients to estimate the difference in attitudes of marijuana use between the states. In the weighted sample, will also compute the standardized differences to evaluate the balance of baseline covariates between the two states. The propensity score model may be adjusted to further minimize some of the residual difference in the distribution of the baseline covariates between the two states.	Up to 1 year
Secondary	Participants' belief in the usefulness of medical marijuana between those who are residents of Texas versus Arizona	The proportion of patients with positive belief will be reported with a 95% confidence interval. Fisher's exact test will be applied to compare the proportion between residents of two states.	Up to 1 year
Secondary	Perception of medical marijuana	Will evaluate the association of demographical, physical, and psychosocial characteristics of patients and their perception of medical marijuana. In order to address this objective, all the specified characteristics will be summarized by descriptive statistics based on patients' perception of medical marijuana (positive or negative attitude); chi-square (or Fisher's exact) test and Wilcoxon rank sum test may be applied to test the associations for categorical and continuous variables, respectively. Logistic regression model may be utilized to evaluate the association of patients' characteristics with their perception of medical marijuana. Summarized reports of all other questions regarding the preference of patients for treatment of pain, anxiety and depression between medical marijuana versus opioids, anti-anxiety, anti-depressant medications, as well as the perception of impact of media on patient's preference in the Marijuana Survey for Patients will be provided.	Up to 1 year

External Links

•   University of Texas MD Anderson Cancer Center Website