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L-TIL Plus Tislelizumab as First-line Treatment in Advanced Malignant Melanoma

Malignant Melanoma Clinical Trial

Official title:
L-TIL Plus Tislelizumab as First-line Treatment in Advanced Malignant Melanoma

Clinical Trial Summary

The main purpose of this study is to evaluate the safety and effectiveness of liquid tumor infiltrating lymphocytes (L-TIL) combined with tislelizumab as the first-line treatment in patients with advanced malignant melanoma. This study plan to include stage III or IV unresectable or metastatic cutaneous or acral malignant melanoma patients, treat with L-TIL 4 cycles with each infusion (3 -10) x10*9/m2 cells, combined with tislelizumab 200mg, iv, Q3W. It is expected that 30 patients will be enrolled in this study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04924413
Study type Interventional
Source Henan Cancer Hospital
Contact Quanli Gao, Ph.D
Phone 0371-65587483
Email zlyygql0855@zzu.edu.cn
Status Not yet recruiting
Phase Phase 2
Start date July 1, 2021
Completion date December 31, 2025
View Details
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