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Male Contraception clinical trials

View clinical trials related to Male Contraception.

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NCT ID: NCT06094283 Recruiting - Male Contraception Clinical Trials

First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males

Start date: December 20, 2023
Phase: Phase 1
Study type: Interventional

A single ascending oral dose(s) study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of YCT-529 in healthy male subjects.

NCT ID: NCT03455075 Recruiting - Healthy Clinical Trials

Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal Men

Start date: April 16, 2018
Phase: Phase 2
Study type: Interventional

This is a Phase IIa multicenter, double-blind, placebo-controlled study in healthy men to evaluate the spermatogenesis suppression after oral administration of Dimethandrolone Undecanoate (DMAU) alone or with Levonorgestrel (LNG) for 12 weeks versus placebo alone.

NCT ID: NCT03452111 Active, not recruiting - Healthy Clinical Trials

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

Start date: October 25, 2018
Phase: Phase 2
Study type: Interventional

The long term objective is to develop a gel to be used as a male contraceptive.

NCT ID: NCT03298373 Active, not recruiting - Healthy Men Clinical Trials

28-Day Repeat-Dose, Dose Escalation Study of 11-β Methyl Nortestosterone Dodecylcarbonate (11β-MNTDC) in Healthy Men

CCN014A
Start date: November 9, 2017
Phase: Phase 1
Study type: Interventional

This is a Phase I multicenter, double-blind, repeat dose, dose-escalating study, in healthy men to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of 11-β Methyl Nortestosterone Dodecylcarbonate (11β-MNTDC).

NCT ID: NCT02994602 Completed - Healthy Men Clinical Trials

Study of Serum Testosterone and Nestorone in Females After Secondary Exposure to Nestorone ® (NES) + Testosterone (T) Combined Gel Applied to Shoulders and Upper Arms in Males

CCN005B
Start date: January 2017
Phase: Phase 1
Study type: Interventional

This is a two-center, open-label study conducted in healthy male and female volunteers at two academic research centers. The study will consist of three single applications of the Nestorone (NES) + testosterone (T) combined gel on the shoulders/upper arms of male participants followed 2 hours later by supervised skin contact by the non-dosed female participants on the application site on days 1, 8, and 15. Effect of Washing or Clothing Barrier to the Application will be assessed.

NCT ID: NCT02927210 Recruiting - Healthy Men Clinical Trials

Injectable DMAU for Male Contraception in Healthy Male Volunteers (CCN015)

DMAU
Start date: December 2016
Phase: Phase 1
Study type: Interventional

This is a Phase I multicenter, double-blind, single dose, dose-ranging study, in healthy men to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics of Dimethandrolone Undecanoate (DMAU) administered as an intramuscular or subcutaneous injection.

NCT ID: NCT02754687 Active, not recruiting - Healthy Men Clinical Trials

Single Dose, Dose-Ranging Study of 11-β Methyl Nortestosterone Dodecylcarbonate (11β-MNTDC) in Healthy Men

CCN014
Start date: April 2016
Phase: Phase 1
Study type: Interventional

The long term objective is to develop a new male hormone 11-β Methyl Nortestosterone Dodecylcarbonate (11β-MNTDC) as a male hormonal contraceptive.

NCT ID: NCT01382069 Completed - Healthy Men Clinical Trials

Phase 1 Study of Dimethandrolone Undecanoate in Healthy Men

DMAUPhase1
Start date: March 2012
Phase: Phase 1
Study type: Interventional

The long term objective is to develop a new male hormone Dimethandrolone Undecanoate (DMAU) as a male hormonal contraceptive. The study has two parts. The first is a dose escalating study in healthy to assess the safety and tolerability of single dose oral administration of DMAUin healthy men.(Completed) The second is to study the safety and tolerability of DMAU after 28 days of repeated daily dosing of DMAU in healthy men. (Currently Recruiting) In both parts the investigators will also study the pharmacokinetics of Dimethandrolone (DMA) in the serum after oral administration of DMAU.